Ingredients that suit you, straight from nature

Lithothamnium calcareum belongs to the group of marine red algae of the Coralineceae family that develop at great depths in the presence of light.
During its growth stage, the algae absorbs nutrients and minerals from the sea by osmosis.
Algae contain 10 to 15 times more trace elements than land plants.
The raw material, calcium, is obtained from the calcareous skeleton.
Calcium is found in calcium carbonate format.

Calcium (Ca) is the most abundant mineral in the human body.
More than 99% of the calcium present in the human body is stored in bones and teeth; The remaining 1% is found in the blood, muscles, and fluids between cells.

Among the sources, calcium is mostly found in dairy products.
Other sources of calcium are almonds, brewer's yeast, broccoli, cabbage, dried figs, kelp, dark leafy vegetables, hazelnuts, oysters, sardines, and canned salmon.

Among the functions, calcium contributes:

• to normal blood clotting.
• to normal energy metabolism.
• to the normal functioning of the muscles.
• to the normal functioning of neurotransmission.
• to the normal functioning of digestive enzymes.
• to the process of cell division and cell differentiation.
• to the maintenance of bones in normal conditions.
• to the maintenance of teeth in normal conditions.

The calcium present in our formulas, specifically in Active Procollagen Plus, comes from the registered brand Aquamin™.
Aquamin™ is a natural multimineral of marine origin, which is obtained from the cytoskeleton of the red algae Lithothamnion spp.

Aloe vera belongs to the genus Aloe, with more than 350 species.
The plant has been used since ancient times in traditional medicine in many countries.
From the plant, aloe is obtained by making cuts in the skin of the fresh leaf and aloe gel obtained from the pulp of Aloe leaves.

The quality and effectiveness of aloe gel is thanks to its polysaccharide content.
Among its main functions, it supports gastrointestinal health and the maintenance of intestinal functions.
This gastroprotective property is due to its anti-inflammatory capacity.

Aloe Vera gel:

• Support gastrointestinal health.
• Helps support digestion.
• Maintenance of bowel functions.
• Helps promote bowel regularity.
• Helps bowel function.
• Contributes to bowel movements.
• Supports regular bowel.
• Supports bowel function for regular bowel movements.
• Contributes to natural defenses against microorganisms.
• Maintenance of the normal immune system.
• Helps increase immunity.
• Helps maintain healthy skin/epithelial layer.
• It helps to increase resistance to psychic charge.
• Helps stimulate metabolism.

Alpha-lipoic acid was discovered more than 40 years ago and, at first, it was thought to be a vitamin.
However, later studies assessed that our body could synthesize it and lost the term "vitamin".
It is an antioxidant substance that is synthesized in human tissues, but, with age, its synthesis gradually decreases.

Alpha lipoic acid is also found in foods, such as red meat, carrots, beets, spinach, and broccoli.
But in this case, the proportion ingested is very small and it is essential to supplement.

This powerful antioxidant protects cells from the damaging effects of free radicals.
Among other functions, it is capable of regenerating other antioxidants such as vitamin C, E and reduced glutathione.
It also helps all the B vitamins convert the carbohydrates, proteins, and fats we eat from food into energy.

Aquamin™ is a natural multimineral of marine origin, which is obtained from the cytoskeleton of the red algae Lithothamnion spp.
Provides calcium.

Lithothamnium calcareum belongs to the group of marine red algae of the Coralineceae family that develop at great depths in the presence of light.
During its growth stage, the algae absorbs nutrients and minerals from the sea by osmosis.
Throughout the algae's life, minerals from seawater accumulate and are stored as carbonate salts in the plant cell wall.
Algae contain 10 to 15 times more trace elements than land plants.
The raw material, calcium, is obtained from the calcareous skeleton.
Calcium is found in calcium carbonate format.

Aquamin™ is sustainably harvested in the crystal clear waters off Iceland's north coast.
Calcium and magnesium account for one-third and more than 2%, respectively, of the more than 70 component minerals of Aquamin's™ total dry mass.

Aquamin™ has an intricate and unique three-dimensional structure shaped by the cell wall of Lithothamnion sp.

Aquamin™ has been shown to have superior bioavailability than other commonly available sources of calcium and has beneficial effects on bones, inflammation, specifically osteoarthritic conditions, digestive health, and cardiovascular health.

One of the characteristics of this calcium is its high bioavailability, since at high pH it is soluble.

Calcium (Ca) is the most abundant mineral in the human body.
More than 99% of the calcium present in the human body is stored in bones and teeth; The remaining 1% is found in the blood, muscles, and fluids between cells.

Among the sources, calcium is mostly found in dairy products.
Other sources of calcium are almonds, brewer's yeast, broccoli, cabbage, dried figs, kelp, dark leafy vegetables, hazelnuts, oysters, sardines, and canned salmon.

Among the functions, calcium contributes:

• to normal blood clotting.
• to normal energy metabolism.
• to the normal functioning of the muscles.
• to the normal functioning of neurotransmission.
• to the normal functioning of digestive enzymes.
• to the process of cell division and cell differentiation.
• to the maintenance of bones in normal conditions.
• to the maintenance of teeth in normal conditions.

Astaxanthin is a carotenoid naturally present in certain algae such as Haematococcus pluvialis, which appears to have beneficial antioxidant properties for health. It is a natural pigment found in certain algae, plants, and some fish such as salmon and shrimp.

It is known for its antioxidant and anti-inflammatory properties and has been researched for its potential health effects, including reducing oxidative stress.

Astaxanthin is a potent antioxidant and is the most important component of krill oil and makes it
Difference over the other omega 3 supplements on the market.

Astaxanthin is a carotene typical of this type of shrimp, it is about 48 times more antioxidant than
common fish oil.
Unlike the other antioxidants, it is able to cross the blood-brain barrier and has a protective effect on the brain, which in turn, spreads throughout the body.

Within the body's cells, it provides protection against the action of free radicals and thus against oxidative stress.
As an antioxidant, astaxanthin has been shown to help stabilize the omega-3 fatty acids in krill oil itself.

Among the benefits studied, it could be mentioned that it contributes to the protection of the skin and could contribute to the protection of eye health by improving visual acuity and reducing fatigue. It could also prevent the oxidation of fatty acids and improve the lipid profile.

Astaxanthin exerts protective effects on the eyes.

Astragalus membranaceus is a very important medicinal plant considered to be a legendary herb.
In traditional Chinese medicine (TCM) it is used in many formulations to treat a wide variety of bodily diseases and disorders.

The main components of Astragalus membranaceus are: Polysaccharides, Flavonoids and Saponins.

Scientific research carried out today is not only focused on the plant, but also on its extracts and components. After many check-ups, many beneficial effects on health are attributed to them, including:

• antioxidants
• Antiinflammatory
• immunoregulators
• Anticancer
• Hypolipidemic
• Antihyperglycemic
• Hepatoprotectors
• Expectorants
• diuretics

In addition to showing significant protection against heart, brain, kidney, intestinal, hepatic and lung lesions in several models of diseases related to oxidative stress.

TA-65®

In 2000, Geron Corporation discovered TA-65®, a molecule from Astragalus, capable of activating telomerase and repairing short telomeres. After 5 years of development and safety studies and with the medical supervision of the Patton protocol designed by its team of scientific experts, T.A. SCIENCES was able to bring the TA-65® to the public.

TA-65® is a dietary supplement based on the root derived from Astragalus membranaceus, patented, which can help maintain or repair telomeres that decrease as people age.
TA-65® is the result of both in vitro and in vivo research in animals and humans.

Telomeres are specialized structures located at each end of the chromosome that protect us from possible fusions and their degradation, thus guaranteeing the stability of chromosomes and the viability of cells.
Among its main functions are to prevent the cell from DNA damage caused by breaks that occur in this area, that is, they protect them from the degradation they suffer over time, from cell division and oxidative damage and inflammation.

Telomere loss is typically attributed to the replication problem of the end part and is clearly accelerated by other factors such as oxidative stress and inflammation. Telomeres shorten as we age, but also because of stress, smoking, obesity, lack of exercise, and poor diet.

Telomerase, on the other hand, is the enzyme responsible for maintaining telomere length.
It stabilizes telomere length by adding DNA repeats at the ends of telomeres, so a functional telomerase is associated with better telomere maintenance.
This highlights its potential role in delaying old age and living healthily since it is capable of preserving telomere length.

Ashwaghanda is an adaptogen, a plant that grows in Asia and Africa used to relieve symptoms of stress.
Ashwagandha extract is a standardized natural extract of Withania somnifera, used in Ayurvedic medicine for more than 3000 years.
The root contains phytosterols with antioxidant and anti-inflammatory activities.

Thus, extracts could help reduce anxiety and improve the body's resistance to stress.
The results of studies also indicate that they could help to fall asleep and improve the quality of sleep.

It can help keep skin healthy by inhibiting the effect of inflammatory cytokines and has been shown to potentially protect against inflammation.

Active Sweet Dreams contains ashwaghanda from a registered trademark, namely KSM-66 Ashwagandha®

Bamboo extract is the richest known source of natural organic silica.
It contains more than 70% silica and more than 10 times the concentration of silica found in the Horsetail plant, which is only about 5-7%.

It is an organic form of silicon that contributes to strengthening teeth, gums, connective tissue, bones and
cartilage.
It is important for the structure of the skin to be healthy and elastic.
In this way, it can also help strengthen nails and hair growth and prevent hair loss.

Silicon plays a fundamental role in the well-being of the skin, ligaments, tendons and
bones.
Provides strength and elasticity to collagen and elastin in connective tissues.
In addition, there are
Keep in mind that collagen is always best taken in the presence of silicon.

Berberine is a phytochemical component extracted from the Barberry plant (Berberis aristata DC).
For thousands of years it has been used in traditional Chinese medicine and Ayurvedic medicine to treat digestive problems and inflammatory conditions.

Berberine has now become popular as the "Ozempic of nature" as it has been shown in numerous studies to have positive effects on the control of parameters related to metabolic syndrome.

• Supports liver health.
• Helps maintain a normal cholesterol level, contributes to a diet to reduce cholesterol.
• Helps improve blood glucose control.
• Helps reduce blood triglyceride levels.

In addition, recent studies suggest that berberine may have positive effects on cellular senescence.
It may have an anti-aging effect by acting to prevent diseases related to cellular aging.

Carotenoids are converted to vitamin A in the body and act as antioxidants.

Vitamin A is fat-soluble.
Depending on whether the food source is an animal or a plant or a plant:

• Vitamin A present in foods of animal origin is called retinol; is one of the most active forms of vitamin A.
• The vitamin A present in fruits and vegetables is called beta-carotene, which is converted into retinol within the body, which makes it an important source of vitamin A.

Among its functions, vitamin A (retinol) contributes:

• to normal iron metabolism.
• to the maintenance of mucous membranes under normal conditions.
• to the maintenance of the skin in normal conditions.
• to the maintenance of vision under normal conditions.
• to the normal functioning of the immune system.
• to the process of cell differentiation.

Betaine, also known as trimethylglycine, is a non-essential nutrient that contributes to the production of hydrochloric acid in the body.
Hydrochloric acid is essential for the absorption of vitamin B12, calcium and iron.

It is synthesized from choline and can also be obtained through the diet.
Food sources such as beets, liver, eggs, fish, legumes, and whole grains.

Betaine is used to treat homocysteinuria, which is the elevation of homocysteine levels in the blood.
Its main function is that it contributes to the normal metabolism of homocysteine.
The beneficial effect is obtained with a daily intake of 1.5 g of betaine.

Betaine contributes:

• to normal homocysteine metabolism.

Bifidobacterium lactis is one of the probiotics present in our body.
It is a probiotic belonging to the lactobacilli group.
It is extracted from milk and fermented vegetables.
Its main function is to digest lactose, sugar, fiber and macronutrients.

It is a bacterial strain that is part of the lactic acid family of families.
It is considered an essential probiotic for health as it contributes to intestinal well-being.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Citrus bioflavonoids (flavonoids) play an essential role in regulating oxidative stress and are an important source of antioxidants.

Boswellic acid is a pentacyclic triterpene naturally produced from Boswellia serrata.
It is an active compound that has been shown to have beneficial effects on health.
It is capable of inhibiting inflammatory enzymes and inflammatory cytokines, which is why its application is used in chronic inflammations.

Boswellia serrata extract (or frankincense tree) is a species of plant native to India and the Middle East.
It is a potential anti-inflammatory that has been traditionally used in folk medicine to treat various chronic inflammatory diseases.
Its active component, boswellic acid, is extracted from the resin of the tree.

In Ayurveda, Boswellia serrata is used to reduce various health problems such as joint pain, inflammation, and respiratory problems (asthma).

It has an antioxidant, soothing and protective effect on the mucous membranes.

• Digestive protector.
  Intestinal soothing.
  It can help maintain the lining of the digestive system.
• Supports mental health.
• Helps keep blood cholesterol at healthy levels.
  Supports heart function.
• Supports lung health.
• Supports menstrual health.
  Supports male sexual health.

Calcium (Ca) is the most abundant mineral in the human body.
More than 99% of the calcium present in the human body is stored in bones and teeth; The remaining 1% is found in the blood, muscles, and fluids between cells.

Among the sources, calcium is mostly found in dairy products.
Other sources of calcium are almonds, brewer's yeast, broccoli, cabbage, dried figs, kelp, dark leafy vegetables, hazelnuts, oysters, sardines, and canned salmon.

Among the functions, calcium contributes:

• to normal blood clotting.
• to normal energy metabolism.
• to the normal functioning of the muscles.
• to the normal functioning of neurotransmission.
• to the normal functioning of digestive enzymes.
• to the process of cell division and cell differentiation.
• to the maintenance of bones in normal conditions.
• to the maintenance of teeth in normal conditions.

Cartidyss® is a type II marine collagen from fish cartilage and glycosaminoglycans (chondroitin, glucosamine, hyaluronic acid).
Cartidyss® with proven efficacy in joint health and skin beauty.
Helps maintain optimal skin structure and properties by promoting dermis densification and dermal extracellular matrix.
It also improves joint health by protecting cartilage.

Collagen is a protein found in almost every part of the body, including skin, bones, joints, muscles, and tendons.
In fact, 30% of all proteins in the human body are made up of collagen.
The function of collagen is to provide flexibility and cohesion in the muscles, that is, it keeps them united and elastic.

Unlike vitamins and minerals, it is not difficult to obtain collagen through food because collagen is found in indigestible areas such as skin, bones, genes, and bones.

There are more than 20 types of collagen, however, the best known are type I, II and III.

• Type I: It is the most abundant type and we find it in the skin.
  Also in bones and tendons.
  Among its main functions is to give elasticity and resistance, as well as it has a support function.
• Type II: Found in joints and cartilage.
  It is a flexible and strong tissue that covers the joints.
  It provides resistance and helps to lubricate these tissues that are under constant pressure.
• Type III: It is a larger molecule than the previous two and is closely related to type I. It is present in muscles, blood vessels, and the lining of the intestines.
  We can also find it in the skin.
  It is responsible for supporting the organs.

As a curiosity, type I and type III collagen have to be hydrolyzed.
This is because it is a very large molecule and our body is not able to digest it.
Hydrolyzed collagen is a type of collagen which has been processed and cut into small particles so that it can be easily absorbed.
Once ingested, this collagen is able to gather and recreate its original shape so that it fulfills its function.
Type II collagen, however, has to be native, meaning it works best if it's unprocessed.

Glycosaminoglycans are an important component present in most vertebrate and invertebrate tissues, mainly in those that have a large extracellular matrix, such as those that form the connective tissues of the neck, cartilage, skin, blood vessels, as well as ligaments and tendons.

Glycosaminoglycans play an important role in cell proliferation and in the repair of damaged tissue, such as that suffered by oxidative stress and/or after a surgical process.
They give cartilage mechanical and elastic properties and give this tissue much of its resistance to compression.
On the other hand, they stimulate fibroblasts to produce more collagen.

Cartidyss®

Clinical studies have demonstrated its efficacy and mechanisms of action:

• Significantly improves the density of the dermis (collagen matrix).
• Significantly reduces wrinkles.
• Improves skin elasticity and dermal hydration.
• Improves joint comfort
• Maintains joint health.

Characteristics:

• Clinically proven for skin and joint health applications.
• High bioavailability and digestibility with low molecular weight peptides.
• Of marine origin and resulting from a sustainable recovery of fish co-products intended for human consumption.
• Low environmental impact compared to other collagen sources (pig, bovine, sheep or poultry)
• Lower effective daily dose than most other sources of hydrolyzed collagen, allowing formulation in multiple dosage forms.
• Complex composition that preserves all the synergistic components naturally present in cartilage.
• GMO-free

Cat's claw, also known as garabato, is native to Peru.
Its anti-inflammatory properties are especially useful for the relief of rheumatism in general.
This action would be related to its ability to neutralize oxidizing substances.
In addition, it plays an important role at the immune level.

CERAMOSIDES® is a patented brand of phytoceramides.
It is an effective source of oral phytoceramides for skin hydration, anti-aging, and hair rejuvenation.
It is a unique patented lipid complex made with 100% wheat, gluten-free and without additives or preservatives.

The action of CERAMOSIDES™ has been scientifically proven by 2 clinical studies:

• CERAMOSIDES^® delivers new ceramides to the skin through the bloodstream and helps restore the water barrier and replenish cracks.
  The skin is left more hydrated and smoother.
• CERAMOSIDES^® is the ultimate moisturizer for smooth, youthful skin, replenishing wrinkles and giving a healthy glow.

Ceramides influence the formation and maintenance of the barrier function of the epidermis.
They are a complex of lipids and fatty acids with a heterogeneous structure.
They play a role in the structure and maintenance of the skin's permeability function.
They account for 50% of lipids and are responsible for keeping water inside the skin.
During aging, the epidermis becomes thinner and weaker and we begin to lose ceramides, resulting in dry, itchy skin and wrinkles.
Hair is also affected, as the reduction of ceramides affects the maintenance and renewal of healthy hair due to its key role as a barrier that protects the hair cuticle.

Phytoceramides are structures similar to natural ceramides, but of plant origin.
They are extracted from corn, rice and wheat.
Wheat germ phytoceramides have a structure almost similar to ceramides found in the skin.

Research has shown that when phytoceramides are digested, they are absorbed and distributed to the epidermis, where they are involved in the synthesis of new ceramides.

Chia is a very small seed, but it contains several properties such as omega 3, fiber, amino acids, vitamins and minerals, among others.

It is a good source of fibre, mainly insoluble fibre, which is that which does not absorb water and passes through the digestive system, favouring the regulation of intestinal transit and the maintenance of beneficial bacterial flora.

They are also rich in an omega 3, alpha linolenic acid, or better known as ALA.
The ALA obtained from the diet is a precursor of EPA and DHA.
However, its conversion is practically insufficient and to obtain DHA, it is more effective to consume oily fish or take a dietary supplement of Omega 3 fatty acids.

Chlorella is a green microalgae that is considered a superfood thanks to its high nutritional value and health benefits.

It is a high-quality protein source that contains essential amino acids, vitamins B, C, E, beta-carotene, iron, calcium, magnesium, zinc, and other minerals.
Being rich in chlorophyll, it has generally been used to provide vitality and energy, in addition, some studies suggest that they can help eliminate toxins.

It is a substance found in human and animal cartilage.
It is commonly used along with glucosamine and other ingredients for osteoarthritis as it could slow down the degradation of cartilage.

It is a sulfated glycosaminoglycan that is usually associated with proteins constituting
high molecular weight aggregates called proteoglycans.
It is an important component present in most vertebrate and invertebrate tissues, mainly in those that have a large extracellular matrix, such as those that form the connective tissues of the neck, cartilage, skin, blood vessels, as well as ligaments and tendons.

Glycosaminoglycans play an important role in cell proliferation and in the repair of damaged tissue, such as that suffered by oxidative stress and/or after a surgical process.
They give cartilage mechanical and elastic properties and give this tissue much of its resistance to compression.
On the other hand, they stimulate fibroblasts to produce more collagen.

Chromium is an essential trace mineral that is found in small amounts in all foods.
The best source of chromium is brewer's yeast.
Others include meat, fish, seafood, and whole grains.

The physiological role of chromium has been studied and it has been proven that it enhances the action of insulin, positively influencing the metabolism of macronutrients and the maintenance of normal blood glucose levels.

Chromium contributes:

• to normal macronutrient metabolism.
• to maintain normal blood glucose levels.

Coenzyme Q10 (CoQ10), also known as ubiquinone, is a vitamin-like substance found within the mitochondria of every cell in the body.

Mitochondria are responsible for extracting approximately 50% of the total energy that comes from the food we eat.
That is why CoQ10 plays a fundamental role in mitochondrial metabolism, specifically it is part of the mitochondrial electron transport chain.
It promotes the conversion of nutrients into ATP (energy molecules).

It is an important antioxidant found in high amounts in organs that need more energy, such as muscles, heart, tissues, and liver.

CoQ10 is found in foods such as organ meats, but cooking tends to destroy it.
Our body also manufactures it, however, as we age, production decreases.
In fact, the lack of energy in older people may, to some extent, be related to this decrease in CoQ10.
That is why its intake in the form of food supplements is so recommended.

It appears that CoQ10 levels may also be lower in people on cholesterol-lowering statins because statins block their synthesis.
On the other hand, studies suggest that CoQ10 can inhibit lipid oxidation by protecting them.

Coleus Forskohlii, also known as Makandi, is an Indian and often rare remedy of Ayurvedic medicine.

Forskolin is a main asset found in the roots of the plant.
It is a potent activator of adenylate cyclase in many tissues, including the thyroid gland.

Collagen is a protein found in almost every part of the body, including skin, bones, joints, muscles, and tendons.
In fact, 30% of all proteins in the human body are made up of collagen.
The function of collagen is to provide flexibility and cohesion in the muscles, that is, it keeps them united and elastic.

Unlike vitamins and minerals, it is not difficult to obtain collagen through food because collagen is found in indigestible areas such as skin, bones, genes, and bones.

There are more than 20 types of collagen, however, the best known are type I, II and III.

• Type I: It is the most abundant type and we find it in the skin.
  Also in bones and tendons.
  Among its main functions is to give elasticity and resistance, as well as it has a support function.
• Type II: Found in joints and cartilage.
  It is a flexible and strong tissue that covers the joints.
  It provides resistance and helps to lubricate these tissues that are under constant pressure.
• Type III: It is a larger molecule than the previous two and is closely related to type I. It is present in muscles, blood vessels, and the lining of the intestines.
  We can also find it in the skin.
  It is responsible for supporting the organs.

As a curiosity, type I and type III collagen have to be hydrolyzed.
This is because it is a very large molecule and our body is not able to digest it.
Hydrolyzed collagen is a type of collagen which has been processed and cut into small particles so that it can be easily absorbed.
Once ingested, this collagen is able to gather and recreate its original shape so that it fulfills its function.
Type II collagen, however, has to be native, meaning it works best if it's unprocessed.

We use two different trademarks of collagen in our formulas.
Active Procollagen Plus contains collagen from the Peptan® brand and the Pro Recovery protein contains collagen from the Natico® brand.

Copper is an essential trace mineral that is present in all tissues of the body.
Various studies carried out in animals and humans have shown that copper is involved in the function of numerous enzymes.
Food sources are oysters, shellfish, whole grains, legumes, nuts, organ meats.
And in lesser quantities it is found in dark leafy vegetables, dried fruit, cocoa, black pepper and yeast.

Among its functions, copper contributes:

• to the maintenance of connective tissue under normal conditions.
• to normal energy metabolism.
• to the normal functioning of the nervous system.
• to normal hair pigmentation.
• to the normal transport of iron in the body.
• to normal skin pigmentation.
• to the normal functioning of the immune system.
• to the protection of cells against oxidative damage.

The American blueberry is a fruit plant of the Ericaceae family native to America.

Currently, it is widely used to protect the urinary tract.
The benefit is that it prevents foreign microorganisms from adhering to the walls of the urine.
Studies suggest that bacteria such as E. coli and the like are prevented from finding a good environment to grow and reduce pain.

The AFSSA (Agence Française de Sécurité Sanitaire des Aliments) admits its use in cases of recurrent urinary tract infections, especially for preventive purposes, with the following claim: the consumption of Vaccinium macrocarpon juice or powder containing 36 mg of PAC produces, in adult women, a decrease in the frequency of urinary tract infections due to E. coli uropathogenines with type P fimbriae.

Curcumin, the main source of curcuminoids from the spice turmeric, has gained increasing global recognition for its multiple health benefits, particularly its antioxidant and anti-inflammatory properties.
As a result, the ingredient is used as a means to support health and longevity.

Specifically turmeric (Curcuma longa):

• It prevents the accumulation of fats and facilitates their elimination by the liver.
• Helps maintain liver health.
• Helps maintain the health of the lungs and upper respiratory tract.
• Helps maintain the effectiveness of the immune system.
• Helps maintain allergy resistance.
• Antioxidant / Protects from free radicals.
• Supports nervous system function.
• Supports heart function.
• Supports blood circulation.
• Helps keep skin healthy.
• It is used to stimulate appetite.
• Helps promote appetite in cases of appetite loss.

We use two types of turmeric from different trademarks in our formulas, depending on the target organ.
Active Detox and Active Revive Celular contain Curcumin C3 REDUCT® turmeric and, Active Memory, contain Longvida® turmeric.

Curcumin C3 Reduct® contains high bioavailability curcumin, demethoxycurcumin and bisdemethoxycurcumin metabolites with 95% tetrahydrocurcuminoids.

Assessed by EFSA as safe for the target population at a dose of 140 mg per day.
Curcumin C3 Reduct® is the focus of clinical research for the management of several lifestyle-related conditions: arthritis, liver disorders, inflammation, hypercholesterolemia, among others, due to its antioxidant and anti-inflammatory properties.

Curcumin, the main source of curcuminoids from the spice turmeric, has gained increasing global recognition for its multiple health benefits, particularly its antioxidant and anti-inflammatory properties.
As a result, the ingredient is used as a means to support health and longevity.

Specifically turmeric (Curcuma longa):

• It prevents the accumulation of fats and facilitates their elimination by the liver.
• Helps maintain liver health.
• Helps maintain the health of the lungs and upper respiratory tract.
• Helps maintain the effectiveness of the immune system.
• Helps maintain allergy resistance.
• Antioxidant / Protects from free radicals.
• Supports nervous system function.
• Supports heart function.
• Supports blood circulation.
• Helps keep skin healthy.
• It is used to stimulate appetite.
• Helps promote appetite in cases of appetite loss.

A primary advantage of Curcumin C3 Reduct is that these health benefits are concentrated and enhanced. In C3 Reduct, curcuminoids are in the form of tetrahydrocurcuminoids (THC).
That is, the product is assimilated directly into the body as beneficial metabolites.
This is important as the metabolites are more bioavailable than the original curcuminoids.
In fact, C3 Reduct is the only EFSA-approved product of its kind on the market.
This is because C3 Reduct delivers active metabolites directly to the body.

D-mannose is a type of sugar present in human metabolism, related to glucose.
It occurs naturally in relatively small amounts.

The characteristic of D-mannose is that it is eliminated by the kidneys and has adhesive effects on bacteria.
In this way, studies suggest that bacteria adhere to D-mannose and are eliminated in the urine, thus relieving discomfort in the urinary tract.

The leaves and root of the Dandelion (Taraxacum officinale) have numerous medicinal properties.
They are rich in vitamins A, K, C, and B complex, minerals such as calcium, magnesium, potassium, zinc, and iron, and nutritional substances such as inulin, lecithin, and choline.

Traditionally, the roots of this herb are employed to help improve digestion and as a liver tonic by stimulating bile production, as well as restoring the hydration of the mucous membranes of the small intestine and the balance of electrolytes.

Dandelion is a powerful prebiotic, i.e. nutrient for beneficial bacteria in the gut microflora.
It also exerts a slight stimulating effect on the muscles of the digestive system, which favors better intestinal transit.

In short:

• Stimulates digestion.
• Contributes to the normal functioning of the stomach and liver.
• Contributes to the functions of the intestinal tract.
• Helps balance the physiological pH of the stomach.
• Contributes to gastrointestinal well-being due to its prebiotic effect.
• It has a beneficial effect on cholesterol values.

Docosahexaenoic acid (DHA) is an omega-3 fatty acid with anti-inflammatory properties and an important role in brain and vision development.
Omega 3 is essential for the body and is obtained through food.
They are mostly found in oily fish such as salmon, mackerel, tuna, herring and sardines.
Also in nuts and seeds (such as flaxseed, chia seeds and black walnuts).

Specifically, DHA is important for maintaining membrane fluidity, an essential property to enable the activity of excitable cells such as neurons.
In the retina, DHA accumulates mainly in the membrane and this fatty acid actively participates in the process of transformation of the light stimulus.
But the greatest importance of DHA has been studied particularly in the brain.
The brain is an organ composed of 60% phospholipids, of which more than half of that percentage is DHA.
It is suggested that it positively influences the functioning of the nervous system and brain.

Docosahexaenoic acid (DHA) contributes:

• to maintain normal brain function.
• to the maintenance of vision under normal conditions.

The beneficial effect is obtained with an intake of 250 mg of DHA.

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) contribute:

• to the normal functioning of the heart.

DAO is the main enzyme in the metabolism of ingested histamine.
It is mostly located in the intestinal epithelium, an area where histamine from the diet is degraded, preventing it from passing into the blood.

What is DAO deficiency?
DAO deficiency is when there is a deficit in the activity of the enzyme DiAminoOxidase (DAO) or when there is an unbalanced proportion between the histamine ingested with food and the ability to metabolize it by this enzyme.
Because of this, histamine is not metabolized or degraded sufficiently, passing into the bloodstream and triggering the different symptoms.

Common symptoms of DAO deficiency include:

• Digestive disorders, such as bloating, flatulence, constipation, or diarrhea.
• Muscle pain and contractures and osteopathic pain.
• Skin disorders, such as dry or atopic skin.
• Headache.
• Non-allergic rhinitis.
• Tinnitus.

What is histamine?
Histamine is a messenger substance that belongs to the group of so-called biogenic amines.
Can
be synthesized by the body itself, however, it can also be obtained naturally, as it is present in many foods.
As a biological messenger substance, histamine has several functions in the body.
As a neurotransmitter, it is involved, among other functions, in the regulation of the sleep-wake rhythm and in the control of appetite, as well as in the capacity for memory and learning.
However, histamine mainly acts as a mediator of inflammatory processes in allergic reactions.

What happens to histamine obtained from food?
Under normal conditions, eating foods containing histamine will be inconsequential, as such food-derived histamines will be rapidly broken down in the gut by the body's own enzyme diamine oxidase (DAO).
When a diet high in histamine is consumed, the activity of this enzyme diamine oxidase (DAO) may not be sufficient, leading to delayed degradation of histamine in the gut.
In addition, alcohol and certain medications can significantly reduce the activity of the DAO enzyme.
When the breakdown of histamine is delayed, its level in the body will increase momentarily.

What foods contain histamine?
In particular, aged or long-stored foods will be high in histamine and other biogenic amines.
Some examples:

• Alcohol, in particular red wine and sparkling wine,
• Cheese
• Seafood, fish and fish sauces
• Raw sausages, such as salami or ham
• Sauerkraut
• Various vegetables: tomatoes, spinach, eggplant
• Various fruits: strawberries, pineapples, bananas.

1-deoxynojirimycin (DNJ) is the standardised active substance extracted from the white mulberry leaf (Morus alba) and has a structure close to that of glucose.
This similarity makes it possible to prevent complex sugars from breaking down and passing into the bloodstream before being used by cells or stored.
Therefore, DNJ prevents a rapid rise in blood glucose levels.
Reducose® is 5 times more concentrated in DNJ than other mulberry extracts on the market.
Reduco has been® shown through scientific studies to convert fast sugars and carbohydrates into slow ones.

• Reducose® blocks enzymes in the upper digestive system that break down sucrose and carbohydrates into glucose, for about 1 hour*.
• This directly lowers blood sugar and insulin variations after meals, supporting a healthy blood sugar level through better "Time Within Range"*
• Reducose® helps maintain a healthy microbiome and has not been shown in clinical studies to cause increased gastric problems*

In addition, white mulberry leaf significantly reduces the breakdown of sugar and starches into glucose causing a better glycemic index.

• Healthier insulin response.
• Prevents the sugar from falling.
• Feeling of fullness for longer.
• Feed the good bacteria.
• Moderate weight loss.
• No unwanted effects.

Active Berberine contains Reducose ®.

Bacopa monnieri is a nootropic herb that has been traditionally used in medicine to improve longevity and cognitive status.
It has also been shown to improve age-related cognitive decline (particularly in the process of speed and memory).

• It can help improve concentration and memory.
• Helps maintain good cognitive function
• It helps maintain memory with declining age and preserve cognitive function.
• Helps peripheral blood microcirculation.
• It contributes to normal blood circulation, which is associated with brain performance.

The Pinus Masoniana is a conifer native to Taiwan.
Pine bark contains natural substances called oligomeric proanthocyanidins (PACs), which are a class of antioxidants that give pine bark its color.
The dry extract of the bark is used worldwide for its antioxidant and anti-inflammatory properties, as well as its health benefits.

The role of antioxidants in Masson pine extract may contribute to neuroprotective activity.

Elastin is usually defined as a protein with structural functions and supports the different tissues of the body.
Its main function is elasticity.

They are fibers specialized in withstanding stretching and straining, and are mainly located in the skin.

Over the years, elastin synthesis decreases, so the skin loses that elasticity and ability to stay firm and smooth.

Enterococcus faecium is a species of good bacteria in the genus Enterococcus.
It is a probiotic that has been shown, among other benefits, to help maintain a balanced and healthy population of gut bacteria.

Enterococcus faecium can help support the gastrointestinal tract, regulate disorders, and build a healthy microbiome.
Its possibility of strengthening the immune system has also been investigated.

Megaflora 9 evo is a probiotic blend that helps regulate the intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

EPA is an omega-3 fatty acid that contributes to heart function.
Omega-3s are essential for the body and are obtained through food, mostly oily fish, nuts and seeds.
Specifically, EPA is a precursor of anti-inflammatory substances that are part of the prostaglandin family.
EPA is especially important for the cardiovascular system, but it can also be effective at the musculoskeletal, joint, dermatological level, etc.
On the other hand, EPA (eicosapentaenoic acid) participates in the modulation of the immune response, helping to reduce inflammation and anatomical-functional damage, showing its anti-inflammatory effect.

El ácido eicosapentaenoico (EPA) y ácido Docosahexaenoico (DHA) contribuyen:

• to the normal functioning of the heart.

• to the normal functioning of the heart.

It is the main active ingredient of the guggul or guggulu.
Guggul is the gum resin obtained from the Commiphora mukul plant.
In Ayurvedic medicine, guggul was used as an anti-inflammatory purifying plant that helped soothe joint pain, skin problems, and maintain a balanced weight.

Later it was seen that this plant extract can contribute to improving blood cholesterol values1 and improving cases of hypothyroidism.

Fermented papaya.
For centuries, Asian and Native Central American cultures have known about the longevity and health benefits of papaya.
The Japanese population has one of the highest life expectancies in the world, which is partly explained by a diet that regularly includes fermented foods.

Immun'Âge is a tasty natural food supplement made using traditional fermentation techniques of non-GMO papayas (Carica), grown by contract farmers in Hawaii.

The Osato Research Institute (Gifu, Japan) has managed to combine the benefits of papaya (Carica) and fermented foods with its patented fermentation process.
This 10-month process transforms the fruit into FPP® (fermented papaya preparation).

It is made using an exclusive fermentation procedure under strict ISO quality controls. It is made without preservatives or chemical additives and no side effects or toxicity have been reported after 20 years on the market.

• Single ingredient: 100% FPP® (fermented papaya preparation) Hawaiian papaya (Carica)

• Strict quality control: Two-stage quality control process for extraction standardization:

  • Amino acid analysis (HPLC)
  • In-vitro measurement of antioxidant power (electron spin)

• Quality certifications

  • ISO 9001:2015 (production)
  • ISO 14001:2015 (environmental)
  • ISO 22000 and FSSC 22000:2018 (highest level of safety in food safety management)

• 100% natural: Papayas certified as non-genetically modified organisms, without preservatives or chemical additives

• Safe: No adverse side effects or toxicity have been reported after 25 years on the market

• Confidence guarantee: Plant-based, gluten-free, dairy-free, soy-free, suitable for people with type 2 diabetes.

• Informed Sport: Has passed the banned substance tests

Specific uses of the P.P.F. ®

A wide range of clinical studies have shown the effectiveness of PPF® in many other cases, such as:

• Airway protection:
  It can help fight infections by reducing the detrimental effect of oxidative stress, thus strengthening the natural defenses of the respiratory mucosa.
  References :

  • Is there a potential application of a fermented nutraceutical in acute respiratory illnesses?
    F. MAROTTA & Co | PMID:22824755

• Protection against oxidative stress in Alzheimer's disease: May help protect against oxidative stress-related damage caused by these diseases.
  References :

  • Oxidative Stress in Patients with Alzheimer's Disease: Effect of Extracts of Fermented Papaya Powder.
    M. BARBAGALLO & Co | Hindawi Publishing Corporation, Mediators of Inflammation, Article ID 624801

• Protection against cardiovascular disease:
  It can help maintain good cardiovascular health by protecting the body against dysfunction of the inner lining of blood vessels.
  References :

  • Cardioprotective effect of a bio fermented nutraceutical on endothelial function in healthy middle-aged subjects.
    F. MAROTTA & Co | PMID:22533427

• Protection against skin aging:
  improved hydration, elasticity and uniformity of the skin; Protection against skin aging.
  References :

  • Testing a quality-controlled fermented nutraceutical on skin aging markers: an antioxidant controlled, double-blind study.
    N. ZERBINATI & Co | PMID:26998011

• Protection against chronic wound infection in type II diabetic patients:
  corrects the deficit in the respiratory bursting capacity of neutrophils in patients with T2D and, consequently, strengthens the body's ability to fight infections.
  It also increases angiogenesis locally, thus favoring the healing process.
  References:

  • Does oral supplementation of a fermented papaya preparation correct respiratory burst function of innate immune cells in type 2 diabetes mellitus patients?
    R. Dickerson & Co | PMID:25268638
  • May Dietary Supplementation Augment Respiratory Burst in Wound-Site Inflammatory Cells?
    A. DAS & Co | PMID:28810801

• Protection against electromagnetic field intolerance syndrome (SICEM):
  decrease in the number and severity of clinical symptoms (headache, fatigue, episodes of tachycardia, insomnia, attention deficit).
  References:

  • Phase I-II study testing the therapeutic effect and stimulating properties of antioxidant defences to patients suffering of Electromagnetic Fields Intolerance Syndrome.
    D. BELPOMME & Co | Functional Foods in Health and Disease 2018;8(2): 122-144 US Patent No.US10993980B2 – "Method for Treating Electrohypersensitivity with FPP®"

Fisetin is one of the antioxidant flavonoids present in small amounts in special fruits and vegetables.
Strawberries have by far the highest content of this compound, followed by apples.
Specifically, strawberries have 5 times more fisetin than apples.
And overall, more than 30 compared to mangoes, kiwis, grapes, tomatoes, onions, cucumbers, and some nuts.

However, the amount of fisetin in these foods is insufficient to provide the beneficial effect and it is necessary to consume food supplements to reach the amount of at least 100 mg per day.

Fisetin has been studied to have beneficial effects on health.
It seems to contribute to the reduction of cell senescence, a process associated with cellular aging.

Hydrolyzed fish cartilage from ray and shark, with high digestibility and bioavailability.
Contains collagen and glycosaminoglycans.

Cartidyss® is a trademark with fish cartilage.
Cartidyss®is a type II marine collagen from fish cartilage and glycosaminoglycans (chondroitin, glucosamine, hyaluronic acid).
Cartidyss® with proven efficacy in joint health and skin beauty.
Helps maintain optimal skin structure and properties by promoting dermis densification and dermal extracellular matrix.
It also improves joint health by protecting cartilage.

Collagen is a protein found in almost every part of the body, including skin, bones, joints, muscles, and tendons.
In fact, 30% of all proteins in the human body are made up of collagen.
The function of collagen is to provide flexibility and cohesion in the muscles, that is, it keeps them united and elastic.

Unlike vitamins and minerals, it is not difficult to obtain collagen through food because collagen is found in indigestible areas such as skin, bones, genes, and bones.

There are more than 20 types of collagen, however, the best known are type I, II and III.

• Type I: It is the most abundant type and we find it in the skin.
  Also in bones and tendons.
  Among its main functions is to give elasticity and resistance, as well as it has a support function.
• Type II: Found in joints and cartilage.
  It is a flexible and strong tissue that covers the joints.
  It provides resistance and helps to lubricate these tissues that are under constant pressure.
• Type III: It is a larger molecule than the previous two and is closely related to type I. It is present in muscles, blood vessels, and the lining of the intestines.
  We can also find it in the skin.
  It is responsible for supporting the organs.

As a curiosity, type I and type III collagen have to be hydrolyzed.
This is because it is a very large molecule and our body is not able to digest it.
Hydrolyzed collagen is a type of collagen which has been processed and cut into small particles so that it can be easily absorbed.
Once ingested, this collagen is able to gather and recreate its original shape so that it fulfills its function.
Type II collagen, however, has to be native, meaning it works best if it's unprocessed.

Glycosaminoglycans are an important component present in most vertebrate and invertebrate tissues, mainly in those that have a large extracellular matrix, such as those that form the connective tissues of the neck, cartilage, skin, blood vessels, as well as ligaments and tendons.

Glycosaminoglycans play an important role in cell proliferation and in the repair of damaged tissue, such as that suffered by oxidative stress and/or after a surgical process.
They give cartilage mechanical and elastic properties and give this tissue much of its resistance to compression.
On the other hand, they stimulate fibroblasts to produce more collagen.

Cartidyss®

Clinical studies have demonstrated its efficacy and mechanisms of action:

• Significantly improves the density of the dermis (collagen matrix).
• Significantly reduces wrinkles.
• Improves skin elasticity and dermal hydration.
• Improves joint comfort
• Maintains joint health.

Characteristics:

• Clinically proven for skin and joint health applications.
• High bioavailability and digestibility with low molecular weight peptides.
• Of marine origin and resulting from a sustainable recovery of fish co-products intended for human consumption.
• Low environmental impact compared to other collagen sources (pig, bovine, sheep or poultry)
• Lower effective daily dose than most other sources of hydrolyzed collagen, allowing formulation in multiple dosage forms.
• Complex composition that preserves all the synergistic components naturally present in cartilage.
• GMO-free

From a nutritional point of view, fish are classified according to their fat content: fatty or oily fish, semi-fatty and lean or white.
Only fatty or semi-fatty fish contain high levels of Omega 3, the best known of which are EPA and DHA.
These fatty acids have been shown to be beneficial to health.

This fish oil has the SLTEX seal, a seal of the Solutex GC company that guarantees the highest criteria of purity and quality when obtaining specialties aimed at human consumption; through the use of a unique supercritical CO2 extraction and purification fluid technology.
It also guarantees Omega 3, both EPA and DHA, in very high purity and concentration.
The high concentration of EPA and DHA means greater absorption and incorporation by our body.

From a nutritional point of view, fish are classified according to their fat content: fatty or oily fish, semi-fatty and lean or white.
Only fatty or semi-fatty fish contain high levels of Omega 3, the best known of which are EPA and DHA.
These fatty acids have been shown to be beneficial to health.

VivoMega™ is a purified omega-3 fish oil oil.
Concentrate with high content of EPA based on triglycerides (TG) made from fish oil.
The specification is a product with a minimum of 90% TG with 2.5 to 5.0 mg/g mixed tocopherols added.
Mixed tocopherol (E306) is of non-genetically modified quality and with preserved identity.

VivoMega™ is sustainable and must not only bring a benefit to the consumer, but also contribute to the protection of the environment.

Flax (Linum Usitatissimum) is a herbaceous plant in the Linaceae family.
Its stem is used to make cloth and its seed, called flaxseed, is used to extract oil and flour (flax powder).

Flaxseeds are high in soluble fiber and lignans, which contain phytoestrogens.
They are also rich in an omega 3, alpha linolenic acid, or better known as ALA.
The ALA obtained from the diet is a precursor of EPA and DHA.
However, its conversion is practically insufficient and to obtain DHA, it is more effective to consume oily fish or take a dietary supplement of Omega 3 fatty acids.

Among the benefits of flax powder:

• Traditionally used to facilitate digestion.
• Helps to promote digestion.
• Helps promote digestion.
• Contributes to digestive comfort.
• Breast Health/Maintains healthy condition of breast tissue.
• The lignans present in Linum usitatissimum offer benefits in intestinal function.
• Helps maintain normal bowel function.
• Contributes to the regularity of bowel function.
• The lignans present in Linum usitatissimum have estrogenic properties and may therefore offer benefits for menopausal health.
• Helps maintain weight.
• Contributes to weight loss in addition to dietary measures.
• Helps reduce appetite.
• Promotes the feeling of satiety after meals.
• Promotes a feeling of fullness and satiety.
• Helps to reduce caloric intake.
• Increases the volume of the stool.
• Promotes intestinal peristalsis.

Boswellia serrata extract (or frankincense tree) is a species of plant native to India and the Middle East.
It is a potential anti-inflammatory that has been traditionally used in folk medicine to treat various chronic inflammatory diseases.
Its active component, boswellic acid, is extracted from the resin of the tree.

In Ayurveda, Boswellia serrata is used to reduce various health problems such as joint pain, inflammation, and respiratory problems (asthma).

Boswellic acid is a pentacyclic triterpene naturally produced from Boswellia.
It is an active compound that has been shown to have beneficial effects on health.
It is capable of inhibiting inflammatory enzymes and inflammatory cytokines, which is why its application is used in chronic inflammations.

It has an antioxidant, soothing and protective effect on the mucous membranes.

• Digestive protector.
  Intestinal soothing.
  It can help maintain the lining of the digestive system.
• Supports mental health.
• Helps keep blood cholesterol at healthy levels.
  Supports heart function.
• Supports lung health.
• Supports menstrual health.
  Supports male sexual health.

Garcinia Cambogia is a plant with a promising role as an adjuvant to the diet.
Their interest is focused on its active component, hydroxycitric acid (HCA), which is thought to block enzymes that will become fat deposits in the body.

Garcinia:

• Contributes to weight control.
• Helps reduce fat storage.
• Reduces the feeling of appetite.
• Helps control body weight.
• Helps reduce feelings of hunger and appetite for treats.
• It helps maintain normal blood sugar and fat levels.

Ginkgo biloba extract is obtained from the leaves of the Ginkgo tree.
The most beneficial components of ginkgo are thought to be flavonoids, which have powerful antioxidant qualities, and terpenoids, which help improve circulation by dilating blood vessels.

Ginkgo biloba supports cognitive function.

Gamma linolenic acid (GLA) is an essential fatty acid of the omega 6 class.
It should be supplied through the diet.
This fatty acid is an essential chemical element that the body must have in order to form necessary elements of its own.

It is an anti-inflammatory that regulates the modulation of the inflammatory response.
GLA is converted to dihomo GLA (DGLA) which is incorporated into the phospholipids of the cell membrane.
It undergoes oxidative metabolism to produce anti-inflammatory eicosanoids.

Promotes cardiovascular health, as well as skin health.
GLA in combination with EPA is needed to improve bone strength.

Glucosamine is a naturally occurring compound found in cartilage, the tough tissue that protects joints.
It is an aminomonosaccharide naturally present in human tissue and is a precursor of glycosaminoglycans and proteoglycans.
It can be said that both favor the development of cartilage tissues.

Glycosaminoglycans are components of the extracellular matrix and play an important role in cell proliferation and in the repair of damaged tissue, such as that suffered by oxidative stress and/or after a surgical process.
They give cartilage mechanical and elastic properties and give this tissue much of its resistance to compression.
On the other hand, they stimulate fibroblasts to produce more collagen.

Proteoglycans promote the development of cartilage tissues, give volume and hydration to the skin and stimulate fibroblasts to produce more collagen, as well as moisturizing the matrix and concealing wrinkles.

Glutamine is the most abundant amino acid in the body and is involved in numerous processes of intermediate metabolism.

Although it is considered a non-essential amino acid because it can be synthesized in the body, it is considered conditionally essential because there are serious clinical situations that can lead to a major deficiency.
Reduced glutamine concentrations are associated with impaired immune function, altered structure and function of the intestinal mucosa and associated lymphoid tissues, decreased oxidative capacity, and altered insulin sensitivity in critically ill patients.

Glutamine is known as an important stimulator of collagen biosynthesis in collagen-producing cells.
Glutamine encourages the production of new cells and slows aging.

Goji berry extract is known as one of the richest sources of vitamins and other nutrients.
It contains more than 18 different amino acids and vitamins such as B1, B2, B6, C and E, all of which are powerful antioxidants that play a role in preventing skin aging.

Grapes are one of the most prized, nutritious fruits rich in vitamin C. Its seeds contain a wide variety of polyphenolic substances that give value to its use in supplementation.

The grape seed extract is obtained from the seeds, which contain antioxidant-rich compounds.
Antioxidants are good allies to protect us against free radicals.

Since ancient times, green tea has been highly prized both as a social beverage and as a medicinal plant.
It has been popularly believed that green tea can help increase metabolic rate, that is, the ability to convert food into energy.
Therefore, its consumption was, primarily, as an adjuvant to weight loss diets.

Now, recent studies have shown that it can have other health benefits thanks to the fact that its active ingredients give it its antioxidant capacity.
Thanks to this antioxidant activity, green tea is able to neutralize free radicals.
As such, it has been linked to other potential benefits for aging.

Green tea (Camellia sinensis L.) is rich in polyphenols, among which catechins stand out, the most abundant being epigallocatechin gallate (EGCG), with high antioxidant power.

Recently, there have been studies that could indicate that green tea may help reduce joint pain and inflammation.

Guggul or guggulu, is the gum resin obtained from the Commiphora mukul plant.
In Ayurvedic medicine, guggul was used as an anti-inflammatory purifying plant that helped soothe joint pain, skin problems, and maintain a balanced weight.

Later it was seen that this plant extract can contribute to improving blood cholesterol values1 and improving cases of hypothyroidism.

Gymnema sylvestre is a shrub that belongs to the Apocynaceae family.
Its leaves are well known in Ayurvedic medicine.
In fact, it is known as gurmar, a Hindi word that means "destroyer of sugar".

Gymnema has become popular around the world due to its potential effects on sugar control.
For this reason, the Journal of Clinical Biochemistry and Nutrition suggests that it has a potential antidiabetic effect thanks to its active ingredient, gymnemic acids.

For this reason, gymnema is used as:

• Support appetite control.
• Support for the control of appetite for sweets.

Choline is an essential nutrient that belongs to the group of B vitamins. It is not a vitamin as it can be synthesized in small amounts in the liver.
Most of the choline found in the body comes from the food you eat.
Among its sources, it can be obtained from meat, eggs and dairy products.
It is also obtained from cruciferous vegetables such as Brussels sprouts, broccoli and cauliflower and some types of beans, nuts, seeds and whole grains.

On the other hand, choline is very important for cell membranes and for producing acetylcholine, a neutrotransmitter.
Therefore, it plays an important role in memory and muscle control.

Among its functions, the hill contributes:

• to normal homocysteine metabolism.
• to normal lipid metabolism.
• to maintain normal liver function.

Recent studies suggest that, in addition to the properties of choline for the proper functioning of organs such as the liver or brain, they can also contribute to maintaining the muscular system and reducing cardiovascular risk.

Hops orhumulus lupulus is a plant belonging to the three species of the genus humulus.
The part used of this plant are the female inflorescences to which a sedative effect is attributed.

The European Medicines Agency (EMA) concluded that, based on its prolonged use, it can relieve mild symptoms of mental stress and help you fall asleep.

In addition, the combination of valerian and hops has been shown to increase the effectiveness of action in both plants.

Hyaluronic acid is a polysaccharide found in the epidermis, connective tissue, cartilage, synovial fluid, eyes, and many other organs and tissues.

As we age, the synthesis of hyaluronic acid decreases and its presence in the body decreases over the years.
This is what causes us to have greater stiffness in the joints, less hydration and lubrication in the cartilage and a less flexible skin full of wrinkles.

It acts as a 'storehouse' for water molecules, so its main function is to retain water and keep the organs that contain it hydrated.

Barberry ("Berberis aristata DC.") is a species of shrub in the Berberidaceae family.
The golden yellow coloration of the stem and bark is due to the presence of berberine.

Barberry extract contains this phytochemical component known as Berberine, which has been shown in numerous studies to have positive effects on the control of parameters related to metabolic syndrome.

• Supports liver health.
• Helps maintain a normal cholesterol level, contributes to a diet to reduce cholesterol.
• Helps improve blood glucose control.
• Helps reduce blood triglyceride levels.

In addition, recent studies suggest that berberine may have positive effects on cellular senescence.
It may have an anti-aging effect by acting to prevent diseases related to cellular aging.

Inulin is a non-digestible carbohydrate that is present in many vegetables, fruits, and cereals.

Inulin and its derivatives (oligofructose, fructooligosaccharides) are generally called fructans.

In addition to being a source of dietary fibre with a low caloric value, its health benefits include the prebiotic, hypoglycemic effect and also improves the bioavailability of calcium and magnesium.

Iodine is a trace mineral and nutrient that occurs naturally in the body.

It is necessary for cells to transform food into energy.
Humans need iodine for the normal functioning of the thyroid, and for the production of thyroid hormones.

Iodized salt is one of the main food sources.
It is followed by shellfish that contain it naturally, as well as fish.

Among the functions, iodine contributes to:

• to normal cognitive function.
• to normal energy metabolism.
• to the normal functioning of the nervous system.
• to the maintenance of the skin in normal conditions.
• normal thyroid hormone production and normal thyroid function.

It is a lichen (between an algae and a fungus that live together and that allows it to resist extreme temperatures).
It was widely used in the nineteenth century in Ireland when there was a famine, and it is also used as a thickener in food.

It has a high content of carrageenan (a type of gelatinous oligosaccharides), which give it a mucilaginous consistency which can help act as a soothing and protective agent for all mucous membranes.

Ispaghula powder, also known as Psyllium, is a type of soluble fiber (80%) that is non-fermentable that comes from the species Plantago ovata.
Psyllium generally refers to the husk of the plant's seed ("husk").
The powder is obtained from the grinding of the shell.

This fiber, when taken along with water, causes it to increase in volume, forming a soft gel that helps soften hard stools in constipation.
The WHO (World Health Organization) and the EMEA (European Medicines Agency) recommend its consumption to combat constipation.

Numerous studies suggest that, in addition to improving intestinal transit, it contributes to improving intestinal function, maintaining a healthy intestine and can also help control blood cholesterol levels.

By way of summary:

• Helps control blood cholesterol levels.
• Contributes to intestinal transit and intestinal function.
• Helps maintain a healthy intestine and facilitate intestinal transit.

Traditional medicine attributes diuretic, antiseptic, carminative and stomach properties to the fruits of the Juniper.
Thanks to its diuretic, antimicrobial and anti-inflammatory activity, it has been traditionally used for the treatment of urinary tract infections.

The chemical composition of juniper essential oil includes about 105 constituents, among those present are monoterpenes (58% essential oil with a content of 20% in α-pinene, 8.7% in limonene, 8.5% in myrcene, among others), tannins (proanthocyanidins, gallocatechin and epigallocatechin) and flavonoids (quercetin, isoquercetin, apigenin and amentoflavone).

It has been described that these three types of elements inhibit the action of bacterial adhesins, contributing to the antimicrobial action of juniper.

The EMA (European Medicines Agency) accepts as an indication: Increase the amount of urine to achieve
Urinary tract lavage as an adjuvant in minor urinary tract disorders.

Kalplea japonica extract contains 50% Resveratrol.

Resveratrol is a naturally occurring polyphenol belonging to the stilbene family usually found in the skin of red grapes, in wine, and in some berries.

Resveratrol's fame stems from the "French paradox" which is a term used to describe the observation that even though the traditional French diet is high in saturated fat, the French have a low incidence of cardiovascular disease compared to other countries with similar diets.
It has been speculated that this could be due to other components that are part of the French diet, such as the resveratrol present in red wine.

Resveratrol has an antioxidant action, like all polyphenols.
This can neutralize free radicals and reduce oxidative stress in cells.

It can help eliminate menopausal symptoms.
Resveratrol has also been reported to act as an activator of sirtuins, genes that are activated during calorie restriction.

Kelp refers to several species of large, brown algae that can grow to enormous sizes far from the deep ocean.
It is a rich source of iodine.

Iodine is a trace mineral and nutrient that occurs naturally in the body.

It is necessary for cells to transform food into energy.
Humans need iodine for the normal functioning of the thyroid, and for the production of thyroid hormones.

Iodized salt is one of the main food sources.
It is followed by shellfish that contain it naturally, as well as fish.

Among the functions, iodine contributes to:

• to normal cognitive function.
• to normal energy metabolism.
• to the normal functioning of the nervous system.
• to the maintenance of the skin in normal conditions.
• normal thyroid hormone production and normal thyroid function.

Krill are small shrimp-like crustaceans that live in the waters of the Atlantic Ocean.
They only live for a year and are one of the cleanest organisms in the ocean.
Their diet comes from algae rich in omega 3 and antioxidants such as astaxanthin.
This is an antioxidant with an absorption 400 times more powerful than vitamin E.

This combination of nutrients differentiates it from fish oil and makes krill oil a unique oil.
Astaxanthin is a natural antioxidant.
It is responsible for the dark red color of the oil.
This natural antioxidant is unique to krill in that fish oil does not contain it.

Most fish oils have other types of fats and their absorption is limited by containing many long-chain fatty acids.
Krill oil, however, contains another type of fat, phospholipids.
This type of fat, whose fatty acids are omega 3, are much smaller and very easily digestible.
In addition, it facilitates the adhesion of omega 3 in tissues more effectively and efficiently compared to triglycerides and ethylesters (from fish oil).

The advantage of krill oil is that it increases the omega 3 index.
Studies show that krill oil more effectively raises the omega-3 index compared to fish oil.
That is why you need less fatty acids in krill oil to obtain the same health benefits.
In particular for cardiovascular health.

Krill occupy the lowest position in the food chain, and their clean habitat prevents krill from accumulating pollutants.
This has been demonstrated after extensive analysis at Superba Krill™ , and it is free of contaminants such as dioxins, furans, PCBs, organochlorine pesticides PBDEs, heavy metals, polycyclic aromatic hydrocarbons, arsenic species, fluorides, trans fatty acids and seaweed toxins.

Superba Krill™ oil is extracted from the Antarctic krill species, Euphausia Superba.
Krill is rich in long-chain omega-3 fatty acids (EPA and DHA), phospholipids (with choline), and astaxanthin.

Superba Krill™ oil comes from a sustainable and pure source.
It is MSC (Marine Stewardship Council) certified as a sustainable fishing product and with 100% traceability.

Omega 3 are a type of essential fatty acids that cannot be synthesized by the body and therefore must be incorporated through the diet.
To meet the daily needs of this nutrient, it is often necessary to resort to the consumption of food supplements, especially in stages when these requirements increase, such as pregnancy.

Long-chain polyunsaturated fatty acids (EPA and DHA) are primarily produced from marine microalgae before entering the fish food chain.
These microalgae have the enzymes necessary to efficiently synthesize DHA, from the fatty acid α-linolenic acid (ALA).
However, the ALA (precursor of EPA and DHA) that is obtained from the diet, produces little DHA in the human body, so to obtain DHA it is more effective to consume oily fish or take a dietary supplement of Omega 3 fatty acids.

Omega-3s are mostly found in oily fish such as salmon, mackerel, tuna, herring and sardines.
They are also found in nuts and seeds (such as flaxseed, chia seeds, and walnuts).

Docosahexaenoic acid (DHA) is an omega-3 fatty acid with anti-inflammatory properties and an important role in brain and vision development.
Eicosapentaenoic acid (EPA), on the other hand, is an omega 3 precursor of anti-inflammatory substances and is especially important for the cardiovascular system, but it can also be effective at the musculoskeletal, joint, dermatological level, etc.

Among the benefits of EPA and DHA we find that:

• They contribute to the normal functioning of the heart.

And specifically, docosahexaenoic acid (DHA) contributes to:

• Maintain normal brain function.
• To maintain vision under normal conditions.

KSM-66 Ashwagandha®, is a full-spectrum brand extract, with the highest concentration of all the major root extracts available on the market today.
It is produced using a unique patented extraction process, based on the principles of "Green Chemistry", without using alcohol or any other chemical solvents.

Ashwaghanda (Withania somnifera) is an adaptogen, a plant that grows in Asia and Africa used to relieve symptoms of stress.

Thus, extracts could help reduce anxiety and improve the body's resistance to stress.
The results of studies also indicate that they could help to fall asleep and improve the quality of sleep.

KSM-66® Award Winner: For several of the factors listed above, KSM-66 received The NutraIngredients Asia 2018 Sports Nutrition Ingredient of the Year award, received the 2016 SFE-Herbal Industry Leader Award, the 2014 Frost & Sullivan "Product Innovation in Botanicals" award, the 2013 "Best Botanical Ingredient" award at Natural Products Expo West, and the 2012 "Innovative Ingredient of the Year" award at Panacea.

In 24 double-blind, randomized, placebo-controlled clinical trials, KSM-66 Ashwagandha® has been clinically shown to:

• Reduce stress, stress-related food cravings, and improve sleep quality.
• Improve memory and cognition.
• Increases endurance, strength and immune function.
• Improve sexual function in both men and women, and testosterone in men.

Why do we use KSM-66 Ashwagandha®?

• KSM-66® is the highest-concentration and most bioavailable full-spectrum root extract on the market today, and it preserves all natural components of the herb in the original balance.
• KSM-66® is the ashwagandha root extract with the most extensive set of research studies and clinical trials.
• KSM-66® has the highest percentage of withanolides of all brand-name root extracts available today.
  It has more than 5% withanolides concentration measured by HPLC.
• KSM-66® is the botanical with the highest number of certifications.
  KSM-66 and its manufacturing have gone through our industry's most thorough inspections and safety assessments for GMP (USP, NSF, NPA-UL, WHO) labels, 100% USDA organic, non-GMO (Non-GMO Project Verified).
  ), gluten-free (by GFCO), no BSCG, Kosher, Halal, HACCP and several other drugs.
• KSM-66® is produced using a one-of-a-kind and one-of-a-kind extraction process, based on the principles of "Green Chemistry", without the use of alcohol or synthetic solvents.
• KSM-66® has negligible levels of Withaferin A, a widely recognized cytotoxic withanolide.
• KSM-66® is GRAS affirmed, vegetarian, safe and stable in storage.

L-arginine is an essential amino acid found naturally in red meat, poultry, fish, and dairy.

L-arginine is converted in the body into a chemical called nitric oxide (NO).
NO causes blood vessels to dilate to improve blood flow.
That is why it is commonly used for circulation.

In addition, it is necessary to produce proteins and is key to maintaining healthy tissues and bones.

Cysteine is a non-essential amino acid.
It is one of the 20 amino acids found in proteins, but it is one of the few amino acids that contain sulfur.
It plays an important role in protein synthesis and the production of antioxidants in the human body.

Cysteine is found in many protein-rich foods, such as meat, eggs, dairy products, legumes, and nuts.
However, the amount of cysteine obtained through the diet may not be enough to cover daily needs, so it is advisable to obtain it through dietary supplements.

It has also been assessed that cysteine can perform the following functions:

It can act in liver protection and is an amino acid that participates in detoxification processes in the body.

• It can act in liver protection and is an amino acid that participates in detoxification processes in the body.
• Sulfur-containing amino acids may contribute to the maintenance of healthy hair, nails, and skin structure.
• Boosts resistance and stimulates hair and nail growth.
• Hair and nail revitalizing agent.
• Contributes to normal hair growth.

And, together with glycine with glutamic acid, vitamins C and E, they synthesize glutathione, a very powerful antioxidant.
It also contributes to the formation of another amino acid such as taurine.

Glycine is a conditionally essential amino acid, that is, our body can synthesize it but in insufficient quantities.
That is why it is important to supplement it with diet.
It is a precursor of many metabolites such as glutathione, an antioxidant molecule responsible for defending the body against external agents.

Among its functions, the best known is that it works as a neurotransmitter.
But it could also be involved in the synthesis of proteins, precursors of molecules (such as glutathione) and elimination of benzoates, which are preservatives present in food.

Lysine is one of the eight essential amino acids, that is, the body cannot synthesize it naturally and it must be obtained through the diet.
Foods that contain l-lysine include lean meats, fish, dairy, eggs and legumes.

L-lysine contributes to the formation of proteins, collagen and muscle tissue.
A deficit causes broken skin, brittle nails, and hair loss.

L-OptiZinc® is a patented form of zinc linked to methionine, with a higher bioavailability and in this form, its absorption is not diminished by the consumption of fibers.
L-OptiZinc® is also a more potent antioxidant than zinc itself.

Zinc is a very important trace mineral that is part of a large number of enzymes and other metabolites, distributed in all organs, fluids and secretions of the human body.

Zinc is present in many foods.
The richest source of zinc is oysters.
They are followed by meat, fish, seafood, as well as zinc-fortified breakfast cereals.
To a lesser extent, it is contained in beans, nuts, whole grains, eggs and dairy products.

Among its functions, zinc contributes:

• to normal acid-base balance.
• to normal carbohydrate metabolism.
• to normal cognitive function.
• to normal DNA synthesis.
• to normal fertility and reproduction.
• to normal macronutrient metabolism.
• to normal fatty acid metabolism.
• to normal vitamin A metabolism.
• to normal protein synthesis.
• to the maintenance of bones in normal conditions.
• to the maintenance of hair in normal conditions.
• to the maintenance of nails in normal conditions.
• to the maintenance of the skin in normal conditions.
• to the maintenance of normal testosterone levels.
• to the maintenance of vision under normal conditions.
• to the normal functioning of the immune system.
• to the protection of cells against oxidative damage.
• to the process of cell division.

Taurine is the second most common amino acid found in the body.
It is a non-essential sulfur amino acid that is considered, like other sulfur amino acids, a powerful antioxidant and stabilizer of cell membranes in situations of oxidative stress.
It can be synthesized in the body from cysteine and vitamin B6.
It is also found in foods such as meat, poultry, eggs, dairy products, fish.

Taurine is used by the body to form bile acids that help break down fats in the small intestine.
It also contributes to excreting bilirubin and cholesterol in the bile.

Although research on taurine has focused mainly on its cardiovascular and neurological functions, current studies show other functions that play an important role in health such as the reduction of inflammation associated with oxidative stress, detoxification and immune function.

Lactobacillus Acidophilus is a type of probiotic found in the human gut, mouth, and vagina.

Among their benefits they can help break down food, absorb nutrients and fight "bad" organisms.
It is commonly used to treat diarrhea caused by antibiotics and to fight excess harmful bacteria in the body.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Lactobacillus paracasei is a probiotic strain that is commonly used in the fermentation of dairy products and probiotics.

Among the benefits it has been associated that Lactobacillus paracasei helps in the balance of the digestive system.
But studies suggest that they may help with immune health and respiratory health.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Lactobacillus plantarum is a probiotic that helps convert sugars (such as lactose) into lactic acid.
It is commonly found in fermented products and, in the body, in saliva.

It helps to improve intestinal balance and can help improve in case of antibiotic use.
On the other hand, studies suggest that they may help maintain the immune system and support weight management.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Lactobacillus salivarius is a bacterium recognized for its probiotic properties.
It is found in the resident microbial population in the digestive tract.

Among its functions, it has the ability to modulate the balance of the intestinal microbiota.
Other studies suggest that it may help stimulate the immune system response, increase enzyme activity at the tract level, produce short-chain fatty acids, and lower pH.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Lactococcus lactis is a health-promoting probiotic found in fermented milk products.
Contributes to digestive and intestinal well-being.

Active Flora contains Megaflora 9 evo is a probiotic blend that helps regulate intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Longvida® is a standardized proprietary curcumin extract that provides free curcumin to target tissues and the brain.

It is a safe, effective, and clinically supported curcumin extract.

Longvida® follows the global regulatory compliance framework, offering superior quality assurance and control parameters, as well as being supported by rigorous traceability and sustainability initiatives and clinical testing.

Longvida® allows for the absorption of free curcumin into the blood and target tissues.
This allows Longvida's curcumin to cross the blood-brain barrier and deliver effective free curcumin in easy-to-administer daily doses, making it Cognitive Curcumin of Choice® ®.

Curcumin, the main source of curcuminoids from the spice turmeric, has gained increasing global recognition for its multiple health benefits, particularly its antioxidant and anti-inflammatory properties.
As a result, the ingredient is used as a means to support health and longevity.

Specifically turmeric (Curcuma longa):

• It prevents the accumulation of fats and facilitates their elimination by the liver.
• Helps maintain liver health.
• Helps maintain the health of the lungs and upper respiratory tract.
• Helps maintain the effectiveness of the immune system.
• Helps maintain allergy resistance.
• Antioxidant / Protects from free radicals.
• Supports nervous system function.
• Supports heart function.
• Supports blood circulation.
• Helps keep skin healthy.
• It is used to stimulate appetite.
• Helps promote appetite in cases of appetite loss.

Lycopene is an organic pigment of the carotenoid type.
It is related to beta-catorene and is found in some fruits and vegetables, but mainly found in tomatoes.

Lycopene is an antioxidant that can help protect cells from oxidative damage and protect against anti-aging.
Among its most popular recommendations of which studies support them, lycopene could help maintain a healthy prostate and maintain healthy cardiovascular health.

Magnesium (Mg) is essential and has a very important role in the structure and function of the human body.
An adult's body contains about 25 grams of magnesium.
More than 60% of all magnesium present in the body is found in the skeleton, and about 27% in the muscles.
It also has a very important function at the nervous level.

Sources legumes, cereals, green leafy vegetables, wheat bran, soybean flour, almonds, cashews, cane molasses, pumpkin seeds, pine nuts, and walnuts.

Magnesium contributes to:

• to reduce tiredness and fatigue.
• to electrolyte balance.
• to normal energy metabolism.
• to the normal functioning of the nervous system.
• to the normal functioning of the muscles.
• to normal protein synthesis.
• to normal psychological function.
• to the maintenance of bones in normal conditions.
• to the maintenance of teeth in normal conditions.
• to the process of cell division.

Manganese is a mineral needed to produce energy and protect cells.
The body also needs manganese to strengthen bones, for reproduction, blood clotting, and to maintain a healthy immune system.

Many foods contain manganese such as whole grains, brown rice, oatmeal and whole-grain bread, clams, oysters, and mussels.
Also in nuts, such as hazelnuts and legumes, such as soybeans, lentils, leafy vegetables, such as spinach and kale, and some fruits, such as pineapple and blueberries.

Among the functions manganese contributes:

• to normal energy metabolism.
• to the maintenance of bones in normal conditions.
• to the normal formation of connective tissue.
• to the protection of cells against oxidative damage.

Megaflora 9 evo is a probiotic blend that helps regulate the intestinal bacterial flora, balancing the populations of lactic fermentative bacteria against pathogenic bacteria.

The bacterial strain blend contains:

• Bifidobacterium lactis W51
• Bifidobacterium lactis W52
• Enterococcus faecium W54
• Lactobacillus acidophilus W22
• Lactobacillus paracasei W20
• Lactobacillus plantarum W1
• Lactobacillus plantarum W21
• Lactobacillus salivarius W24
• Lactococcus lactis W19

The improvement of intestinal balance prevents bacterial overgrowth, the development of Candidas and Clostridia responsible for alterations that affect the motility and absorption of nutrients.
Megaflora 9 evo also helps to maintain the integrity of the intestinal mucosa by promoting the epithelial barrier function, which can be altered by various causes such as food intolerances that make the mucosa more permeable, altering the processes of absorption of nutrients and the passage of toxic substances into the body.
All the strains that are part of Megaflora 9 evo have demonstrated their ability to interact at the immune system level.
Some of them stand out for their ability to increase the production of IL-10, a regulatory and anti-inflammatory cytokine.

Megaflora 9 evo uses a novel and unique technology called ProbioAct® (Probiotic Activity) that increases the half-life and efficacy of probiotics.

ProbioAct® technology is a blend of active ingredients that protect and nourish the bacteria in the mixture.
In this way, it is possible to increase:

• Product shelf life: survive at room temperature and controlled humidity.
• Survival of bacteria in the gastrointestinal tract: protects live and intact bacteria so that they arrive alive at the acidic pH of the stomach and the alkaline pH of the intestine.
• The activity of beneficial bacteria in the gut: This is the ability to make the bacteria arrive alive at the target organ, the intestines.
  ProbioAct® improves the metabolic activity of bacterial strains that, when they reach the intestines, produce lactic acid, short-chain fatty acids, and other metabolites.
  These are essential, not only for their regulatory action on the intestinal flora, but also as an indicator of the activity of bacteria.
  In addition, it provides nutrients so that bacteria can colonize and multiply quickly and effectively.

ProbioAct® synergizes the effect of the probiotics in Megaflora 9 evo by optimizing the results noticed by the consumer.
Consequently:

• Megaflora 9 evo has shown that it can counteract dysbiosis phenomena by rebalancing the intestinal flora, maintaining the barrier effect and promoting the integrity of the intestinal mucosa, which allows the maintenance of absorption processes and homeostasis between the individual and their intestinal microbiota.
• The bacterial strains of Megaflora 9 evo have been shown to be able to inhibit the Candida albicans present in the intestine that is associated with intestinal candidiasis.
• Megaflora 9 evo has also been shown to have a potent growth inhibiting capacity of Clostridium difficile, with a reduction in the production of toxins A and B, essential for the pathogenicity of the bacterium involved in many intestinal disorders.
• The average life of the product is 48 months at 25ºC.
• The survival of bacteria in the intestinal tract.
• High activity of bacteria in the intestine.

Melatonin is an endogenous hormone produced by the pineal gland and its synthesis is regulated by light/dark, that is, it is inactivated by light and activated by darkness.
In fact, if we want to produce melatonin properly, we need to lie down without light entering, because it blocks its synthesis.

This hormone is synthesized from the amino acid tryptophan by hydroxylacon and decarboxylation reactions to produce serotonin and melatonin.
Vitamins and minerals are necessary as cofactors in this biological process and, if we have deficits, we may not be able to synthesize the amount necessary to fall asleep.

Among the functions, melatonin contributes:

• to relieve the subjective feeling of jet lag.
• to reduce the time needed to fall asleep.

Active Sweet Dreams contains melatonin from the Melotime™ brand.

Melissa officinalis is an aromatic herb in the same family as mint.
Lemon balm has been famous for years to relieve symptoms derived from digestive problems and to help and support relaxation.

From this plant, dried leaves are used, whose main components are essential oils, flavonoids and phenolic acids, among which rosmarinic acid stands out.
The European Pharmacopoeia recommends that the dry extract of the leaf contain a minimum of 2% rosmarinic acid to ensure the quality of lemon balm and preparations containing this plant.

Melotime™ is a patented, timed-release melatonin nutraceutical ingredient to provide sustained 8-hour sleep.
Melotime ™ is systematically released during the 8 hours of sleep, releasing the first 50% of the dose in the first hour and then the subsequent dose is released every 1 hour.
Because of this release profile, the correct dose of melatonin is achieved without causing feelings of drowsiness the next morning.

Melatonin is an endogenous hormone produced by the pineal gland and its synthesis is regulated by light/dark, that is, it is inactivated by light and activated by darkness.
In fact, if we want to produce melatonin properly, we need to lie down without light entering, because it blocks its synthesis.

This hormone is synthesized from the amino acid tryptophan by hydroxylacon and decarboxylation reactions to produce serotonin and melatonin.
Vitamins and minerals are necessary as cofactors in this biological process and, if we have deficits, we may not be able to synthesize the amount necessary to fall asleep.

Among the functions, melatonin contributes:

• to relieve the subjective feeling of jet lag.
• to reduce the time needed to fall asleep.

Benefits & advantages Melotime™.

• 8 hours of sustained sleep: Its sustained release profile helps to sleep 8 hours without any problems and its effects begin to diminish in the body after 6 hours of administration.
  Relieve the subjective feeling of jet lag.
• Restores the natural sleep pattern: Its unique release profile not only helps you fall asleep gradually but also wake you up eventually, which is seen in natural sleep patterns.
• Sleep Health: The melatonin in Melotime ™ improves subjective sleep quality, as well as some aspects of objective sleep quality.

Memophenol™ is a mixture of flavonols and stilbenes from grapes and anthocyanins present in wild blueberries.

Clinical studies have shown that the synergistic association of these polyphenols favors plasticity and brain microcirculation, as well as helping to reduce oxidative stress, one of the causes of brain aging.

Memophenol™ is a proprietary formula rich in essential polyphenols to improve cognitive performance and memory.
It combines two noble fruit extracts, the best sources of bioavailable polyphenols for synergistic activity:

• The Champagne grape (Vitis vinifera L.), 5 times richer in monomers than other grape species.
  These are small polyphenols that can be assimilated more easily by the body.
• Canadian blueberries (Vaccinium), which contain active molecules that are complementary to those in grapes, making it more effective.

The formula combines these two extracts to have a synergistic action on neuroprotection.
Memophenol™ provides the best source of scientifically proven essential polyphenols to support cognition with demonstrated bioavailability.

Memophenol™, twice patented and backed by science and claims, is a highly polyphenol-rich formula clinically proven to improve learning and memory.

MenaQ7® is a vitamin K2 as menaquinone-7 (MK-7) is the most bioavailable, longest-lasting, and most bioactive form of vitamin K. MenaQ7® is the ONLY effective vitamin K supplement within current RDAs, which has been shown to be safe and effective at only 45 mcg daily.

MenaQ7® is the only clinically validated and patented vitamin K2 like MK-7 available on the market today.
In addition, MenaQ7® varieties are suitable for vegans and vegetarians, free of gluten, dairy, soy and other known allergens.

Vitamin K is a fat-soluble vitamin that occurs naturally in two forms: vitamin K1 (phylloquinone) and vitamin K2.
Both vitamins have the same structure, the difference lies in the active part of the molecule that determines its action and half-life.

The source of K1 in the diet is found in leafy greens such as spinach, broccoli, Brussels sprouts, cabbage, and lettuce.
Vitamin K2, a term used for a group of compounds called 'menaquinones', is found mainly in dairy products.

In the body, vitamin K1 is concentrated in the liver and is essential for blood clotting and has a half-life in the body of 1:30h.
K2, on the other hand, has a half-life of 72 hours, so it allows proteins to be activated outside the liver and fulfill its function in the activation of bone proteins.
As such, vitamin K2 is found in extrahepatic tissues such as bones, cartilage, and arteries, where it plays an important role in regulating calcium metabolism.

Among its functions, vitamin K contributes:

• to normal blood clotting.
• to the maintenance of bones in normal conditions.

Methylsulfonylmethane, known as MSM, is an organic form of sulfur that helps strengthen connective tissue.
This compound is the third most abundant nutrient in the human body and is found in all vertebrates.
Some foods such as meat, vegetables, and dairy products also contain MSM.

Sulphur is an essential nutrient for the body, but the recommended daily intake has not been established.
In the body, sulfur is found in connective tissues such as joints, is necessary for the formation of proteins, is a component of sulfur-containing amino acids, and is a component of enzymes and hormones.

MSM is a chemical found naturally in humans, as well as in some green plants and animals, rich in sulfur, which is essential to connective tissues, skin and hair, and helps build and renew connective tissue.

OptiMSM® is a registered trademark of MSM present in our Active Procollagen Plus product.

MGCPQQ® is the registered trademark of PQQ.

PQQ, or pyrroloquinoline quinone, is a cofactor and natural compound found in some foods, such as tofu, parsley, and green tea.
It is known for its antioxidant and anti-inflammatory properties and has been researched for its potential health effects.
It is a molecule associated with different biological processes such as reproduction, growth, aging and mitochondrial biogenesis.
According to recent studies, it can help increase the number of mitochondria in cells.

MGCPQQ® is a naturally occurring pure source of pyrroloquinoline quinone (PQQ) disodium salt, which is naturally found in small amounts in plants and meats.
MGCPQQ® is a water-soluble, reddish-brown powder that is harvested using Mitsubishi Gas Chemical's proprietary fermentation process.
The ingredient is registered on the European Union's list of new food ingredients.

MGCPQQ® has been studied in dozens of in vitro and in vivo clinical trials.
Mitsubishi Gas Chemical's proprietary fermentation process for harvesting MGCPQQ® naturally is well-controlled and well-documented and certified as safe.

Milk thistle (Silybum marianum) is one of the medicinal plants used for centuries to care for the liver and digestive discomfort related to liver functions.
Its active component is silymarin, which is attributed with antioxidant properties.

Silymarin, thanks to its antioxidant action, can help promote the secretion of bile.
In other words, it contributes to liver detoxification.

• Liver health support.
• Contributes to liver protection.
• Contributes to liver detoxification.
• Useful for maintaining physiological purifying functions.
• Helps maintain cardiovascular health.
• It promotes digestion and purification of the body.

Monacolin K is a metabolite obtained from the fermentation of red rice with the yeast Monacus purpureus, traditionally used in Chinese medicine to lower blood lipid levels.

Red yeast rice could contain compounds that would lower cholesterol levels since its molecule has a chemical structure very similar to lovastatin, a drug used for high cholesterol.

Scientific studies have shown that monacolin k has a similar effect to lovastatin in improving the lipid profile, but with fewer side effects.

Berry extract can come from different types of berries.

OptiBerry® is a complex of standardized berry extracts with antioxidant properties thanks to its composition in "anthocyanins", derived from elderberry, blueberry, blueberry, raspberry seeds and wild strawberry.

The OptiBerry® brand, thanks to its enhanced antioxidant protection, has been specifically studied for its many benefits.
Among them, it contributes to cardiovascular health, and cognitive, neuronal and eye health.
Possible effects on its anti-angiogenic, anti-cancer and anti-diabetic properties have also been seen.

OptiBerry® exhibits high antioxidant efficacy as evidenced by its Oxygen Radical Absorbance Capacity (ORAC) values.

Naticol® is a range of bioactive and bioavailable marine collagen peptides of natural origin.
Specifically, it is a fish collagen.

Naticol ® is extracted from the skin of the fish and then made bioavailable using a unique process specifically developed by Weishardt.
This process is divided into 2 steps: collagen extraction followed by targeted enzymatic hydrolysis.
It is a product endowed with a unique collagen peptide profile.
It is much easier to digest compared to porcine and bovine collagen.

The superior quality of Naticol® is guaranteed by its high level of purity and excellent neutral sensory properties.
It is made up of more than 99% protein in dry form and is a white powder with a neutral taste and odor.

Collagen is a protein found in almost every part of the body, including skin, bones, joints, muscles, and tendons.
In fact, 30% of all proteins in the human body are made up of collagen.
The function of collagen is to provide flexibility and cohesion in the muscles, that is, it keeps them united and elastic.

Unlike vitamins and minerals, it is not difficult to obtain collagen through food because collagen is found in indigestible areas such as skin, bones, genes, and bones.

There are more than 20 types of collagen, however, the best known are type I, II and III.

• Type I: It is the most abundant type and we find it in the skin.
  Also in bones and tendons.
  Among its main functions is to give elasticity and resistance, as well as it has a support function.
• Type II: Found in joints and cartilage.
  It is a flexible and strong tissue that covers the joints.
  It provides resistance and helps to lubricate these tissues that are under constant pressure.
• Type III: It is a larger molecule than the previous two and is closely related to type I. It is present in muscles, blood vessels, and the lining of the intestines.
  We can also find it in the skin.
  It is responsible for supporting the organs.

As a curiosity, type I and type III collagen have to be hydrolyzed.
This is because it is a very large molecule and our body is not able to digest it.
Hydrolyzed collagen is a type of collagen which has been processed and cut into small particles so that it can be easily absorbed.
Once ingested, this collagen is able to gather and recreate its original shape so that it fulfills its function.
Type II collagen, however, has to be native, meaning it works best if it's unprocessed.

Natursyn™ is a patented formula of different components: fatty acids, phytosterols, lignans and antioxidants, obtained from different oils and plant extracts, which act synergistically helping to prevent hair loss caused by different factors.

The fatty acids present in Natursyn™ oil come from the seeds of flax, wheat germ, borage and saw palmetto (Serenoa repens), the latter being the main active ingredient.
Extracts from pine bark and rye flowers complete this formula.

In a clinical evaluation, a daily intake of 600 mg of NaturSYN™ Beaulixir was administered for 6 months and as a result a reduction in hair loss and improvement in hair quality and appearance were observed.
Concretely:

• 93% saw an overall reduction in hair loss
• 88% experienced reduced oily hair
• 83% reported thicker, fuller hair
• 90% felt their hair stronger and have noticed a better styling effect

On the other hand, it was also observed:

• 89% noticed an improvement in nail strength
• 72% saw an increase in skin smoothness and a reduction in oily skin.

In general, women with a tendency to oily hair:

• Reduction of sebum in the hair follicle
• Improved oxygenation due to reduction of blocked fat in the hair follicle
• Reduction of hair heaviness

In hair loss:

• Re-densification of affected areas
• Improved hair thickness with consequent improvement in volume and density
• Visible improvement in hair density and quantity
• The most hydrated and shiny hair

Omega 3 are a type of essential fatty acids that cannot be synthesized by the body and therefore must be incorporated through the diet.
To meet the daily needs of this nutrient, it is often necessary to resort to the consumption of food supplements, especially in stages when these requirements increase, such as pregnancy(1).

Long-chain polyunsaturated fatty acids (EPA and DHA) are primarily produced from marine microalgae before entering the fish food chain.
These microalgae have the enzymes necessary to efficiently synthesize DHA, from the fatty acid α-linolenic acid (ALA).
However, the ALA (precursor of EPA and DHA) obtained from the diet produces little DHA in the human body, so to obtain DHA it is more effective to consume oily fish or take a dietary supplement of Omega 3 fatty acids(2).

Omega-3s are mostly found in oily fish such as salmon, mackerel, tuna, herring and sardines.
They are also found in nuts and seeds (such as flaxseed, chia seeds, and walnuts).

Docosahexaenoic acid (DHA) is an omega-3 fatty acid with anti-inflammatory properties and an important role in brain and vision development.
Eicosapentaenoic acid (EPA), on the other hand, is an omega 3 precursor of anti-inflammatory substances and is especially important for the cardiovascular system, but it can also be effective at the musculoskeletal, joint, dermatological level, etc.

Among the benefits of EPA and DHA we find that:

• They contribute to the normal functioning of the heart.

And specifically, docosahexaenoic acid (DHA) contributes to:

• Maintain normal brain function.
• To maintain vision under normal conditions.

OptiBerry® is a complex of standardized berry extracts with antioxidant properties thanks to its composition in "anthocyanins", derived from elderberry, blueberry, blueberry, raspberry seeds and wild strawberry.

The OptiBerry® brand, thanks to its enhanced antioxidant protection, has been specifically studied for its many benefits.
Among them, it contributes to cardiovascular health, and cognitive, neuronal and eye health.
Possible effects on its anti-angiogenic, anti-cancer and anti-diabetic properties have also been seen.

OptiBerry® exhibits high antioxidant efficacy as evidenced by its Oxygen Radical Absorbance Capacity (ORAC) values.

OptiMSM® is a registered trademark of MSM.

Methylsulfonylmethane, known as MSM, is an organic form of sulfur that helps strengthen connective tissue.
This compound is the third most abundant nutrient in the human body and is found in all vertebrates.
Some foods such as meat, vegetables, and dairy products also contain MSM.

Sulphur is an essential nutrient for the body, but the recommended daily intake has not been established.
In the body, sulfur is found in connective tissues such as joints, is necessary for the formation of proteins, is a component of sulfur-containing amino acids, and is a component of enzymes and hormones.

MSM is a chemical found naturally in humans, as well as in some green plants and animals, rich in sulfur, which is essential to connective tissues, skin and hair, and helps build and renew connective tissue.

OptiMSM® is the result of years of research, development, and continuous improvement.
It has a well-documented safety record and has been studied in a wide variety of investigations.

• Joint Health: In studies, OptiMSM®has been shown to stimulate a significant reduction in pain and deterioration of the cartilage matrix in the joints.
  OptiMSM's® ability to improve mobility and modify the immune response was also revealed.
• Inflammation: Researchers have observed that OptiMSM®can modify pro-inflammatory mechanisms to relieve exercise-induced pain and support antioxidant levels in the body.
  Properties found in OptiMSM®can help prevent the buildup of oxidative damage that develops through aging and stress in the body.
• Safety and effectiveness: Well-documented and studied for safety and efficacy, OptiMSM is considered safe for humans and animals.
  There is no known evidence of interactions between OptiMSM and pharmaceuticals, herbs, vitamins, or minerals.

Why OptiMSM®?

• Unmatched purity: A patented multi-stage distillation process ensures a product with 99.9% purity to ensure consistent, high-quality MSM.
• Safety: The only vegan, non-GMO, gluten-free, allergen-free, and shellfish-free MSM, designated GRAS, Kosher and Halal certified, backed by extensive toxicological data.
• ISO 9001:2015, FSSC 220000 certification, HACCP and cGMP compliance.

Oranges are obtained from the Citrus sinensis plant, commonly known as orange tree.
This tree is native to Southeast Asia and is now found in temperate climates around the Mediterranean.

Orange extract is obtained from the fruit of this tree, the orange.
Its active compound is Hesperidin.
Orange tree extract is an antioxidant component that provides vitamin C, which can contribute to the maintenance of healthy bones and teeth.
It also contributes to the normal formation and maintenance of collagen.

Cocoa (Teobroma cacao L.) is the seed of the fruit of the cocoa tree and is the main ingredient in chocolate. Cacao, which the colonizers brought from America, literally means "the food of the gods", used for centuries by the Indians to increase energy and improve mood.

With more than 300 identifiable active ingredients, it is one of the most suggestive foods.
This seed is rich in flavonoids such as epicatechins and catechins, substances with antioxidant capabilities.

Due to its low fat content (semi-defatted), it provides few calories.
It contains no added sugars or sweeteners.
From organic farming.

Passionflower was a plant used among Native Americans of various Aztec peoples.
When it arrived in Europe, they called it Passiflora, which, in Latin means "flower of passion" or "flower of suffering" since it was used to commemorate the suffering and passion of Christ.
It is a plant that was traditionally used as an anxiolytic and tranquilizer.

Its active ingredient is mainly due to flavonoids.
Both the European Medicines Agency (EMA) and the European Scientific Cooperative on Phytotherapy (ESCOP) recognize that passionflower can be used to relieve mild symptoms of mental stress and nervousness and help to fall asleep and promote sleep.
Based exclusively on its traditional use.

This protein isolate obtained from peas (Pisum Sativum), provides this product with a high content of essential amino acids.
Particularly rich in branched-chain amino acids (each daily dose provides 3.4 g), leucine, isoleucine and valine, which play an important role in muscle protein synthesis.

Despite being of plant origin, it has a high biological value, which means that it is easily absorbed by the body.
In addition, it is very light and easy to digest.
No
It produces a heavy digestion like animal proteins and does not provide unwanted substances to the body such as toxins or additives.

Proteins contribute to preserving and increasing muscle mass and maintaining bones under normal conditions.

For each dose of product (40g) it provides 23g of protein.
This protein is indicated for:

• Those who want to increase the protein intake of their diet.
• Highly recommended for athletes after a workout as it can restore and promote muscle mass.
• For people who want to control their weight.
• For seniors with swallowing or feeding problems.
• To recover from a period of convalescence.
• For people who are in times of higher protein demand (pregnancy, menopause, osteoporosis, muscle weakness, growth).

It is a protein suitable for diabetics, hypertensives, vegans and vegetarians.

It does not contain milk, fructose, lactose, soy, gluten, nuts or other ingredients or allergens.
It does not contain sweeteners, colorants or sulfites.

This product has the advantage that its proteins do not come from allergenic sources such as milk or soy, and that despite being of natural origin,
The plant has a high biological value (in relation to the WHO/FAO/UNU standard), although it could be supplemented with foods rich in cysteine and methionine.

They do not contain phytoestrogens like soy nor are they obtained from genetically modified organisms.

Peptan® is the leading brand of collagen peptides (also known as hydrolyzed collagen) that has been shown in scientific studies to have multiple health benefits.
Peptan® is a collagen from fish.

Peptan® contains 18 amino acids, the building blocks of our tissues and the main building block of proteins.
Glycine, proline, and hydroxyproline account for about 50% of Peptan's® total amino acid content (the concentration of glycine and proline in Peptan® is 10 to 20 times higher than in other proteins).
As a result, Peptan® possesses multifunctional properties that cannot be found in other protein sources.

Peptan's® range of collagen peptides are safe, bioactive and developed using an optimised hydrolysation process, making collagen peptides highly bioavailable and providing specific benefits in key connective tissues of the human body.

To ensure excellent bioactivity, it is critical that collagen reaches the target tissues as efficiently as possible and is highly bioavailable.

Peptan® is easily digested and absorbed very well. Peptides reach the bloodstream within an hour of ingestion.
From the blood, peptides (containing hydroxyproline, a unique amino acid) are transported to target tissues, e.g. skin, bones and cartilage, where they send a signal to local cells and help the cells improve their function.
This functional adaptation is the basis of the health benefit experienced by the consumer.
This means high bioavailability.

Collagen is a protein found in almost every part of the body, including skin, bones, joints, muscles, and tendons.
In fact, 30% of all proteins in the human body are made up of collagen.
The function of collagen is to provide flexibility and cohesion in the muscles, that is, it keeps them united and elastic.
Collagen is a triple helix of alpha chains of amino acids that create solid fibers that are used for the structure of the body.
In essence, it is the ingredient that possesses everything: a key structural protein that ensures the cohesion, elasticity and regeneration of all our connective tissues, strengthening the musculoskeletal system and the integrity of our skin.

Unlike vitamins and minerals, it is not difficult to obtain collagen through food because collagen is found in indigestible areas such as skin, bones, genes, and bones.

There are more than 20 types of collagen, however, the best known are type I, II and III.

• Type I: It is the most abundant type and we find it in the skin.
  Also in bones and tendons. Among its main functions is to give elasticity and resistance, as well as it has a support function.
• Type II: Found in joints and cartilage.
  It is a flexible and strong tissue that covers the joints.
  It provides resistance and helps to lubricate these tissues that are under constant pressure.
• Type III: It is a larger molecule than the previous two and is closely related to type I. It is present in muscles, blood vessels, and the lining of the intestines.
  We can also find it in the skin.
  It is responsible for supporting the organs.

As a curiosity, type I and type III collagen have to be hydrolyzed.
This is because it is a very large molecule and our body is not able to digest it.
Hydrolyzed collagen is a type of collagen which has been processed and cut into small particles so that it can be easily absorbed.
Once ingested, this collagen is able to gather and recreate its original shape so that it fulfills its function.
Type II collagen, however, has to be native, meaning it works best if it's unprocessed.

The phospholipids in krill oil are mostly found in the form of phosphatidylcholine.
Choline is an essential vitamin-like nutrient that contributes to the normal functioning of cells.
It can be part of neurotransmitters (acetylcholine), cell membrane signaling (phospholipids), lipid transport (lipoproteins) and mytyl group metabolism (homocysteine reduction).

Phospholipids are able to release fatty acids more effectively compared to phospholipids.
triglycerides.
They are amphipathic, that is, they are soluble in both hydrophilic and hydrophobic media.
This makes them easier to assimilate and absorb by the body.
They are easy to digest and facilitate the adhesion of omega-3s to tissues more effectively and efficiently compared to triglycerides and ethylesters (from fish oil).

Phospholipids are able to release fatty acids more effectively compared to triglycerides.
They are amphipathic, that is, they are soluble in both hydrophilic and hydrophobic media.
This makes them easier to assimilate and absorb by the body.
They are easy to digest and facilitate the adhesion of omega-3s to tissues more effectively and efficiently compared to triglycerides and ethylesters (from fish oil).

The phospholipids in krill oil are mostly found in the form of phosphatidylcholine.
Choline is an essential vitamin-like nutrient that contributes to the normal functioning of cells.
It can be part of neurotransmitters (acetylcholine), cell membrane signaling (phospholipids), lipid transport (lipoproteins) and mytyl group metabolism (homocysteine reduction)

Ceramides influence the formation and maintenance of the barrier function of the epidermis.
They are a complex of lipids and fatty acids with a heterogeneous structure.
They play a role in the structure and maintenance of the skin's permeability function.
They account for 50% of lipids and are responsible for keeping water inside the skin.
During aging, the epidermis becomes thinner and weaker and we begin to lose ceramides, resulting in dry, itchy skin and wrinkles.
Hair is also affected, as the reduction of ceramides affects the maintenance and renewal of healthy hair due to its key role as a barrier that protects the hair cuticle.

Phytoceramides are structures similar to natural ceramides, but of plant origin.
They are extracted from corn, rice and wheat.
Wheat germ phytoceramides have a structure almost similar to ceramides found in the skin.

Research has shown that when phytoceramides are digested, they are absorbed and distributed to the epidermis, where they are involved in the synthesis of new ceramides.

CERAMOSIDES® is a patented brand of phytoceramides.
It is an effective source of oral phytoceramides for skin hydration, anti-aging, and hair rejuvenation. It is a unique patented lipid complex made with 100% wheat, gluten-free and without additives or preservatives.

The action of CERAMOSIDES™ has been scientifically proven by 2 clinical studies:

• CERAMOSIDES^® delivers new ceramides to the skin through the bloodstream and helps restore the water barrier and replenish cracks.
  The skin is left more hydrated and smoother.
• CERAMOSIDES^® is the ultimate moisturizer for smooth, youthful skin, replenishing wrinkles and giving a healthy glow.

Polygonum cuspidatum, a plant rich in resveratrol. Resveratrol is a naturally occurring polyphenol belonging to the stilbene family usually found in the skin of red grapes, in wine, and in some berries.

We can find resveratrol in the vine plant (Vitis vinifera) contains resveratrol, but the roots of Polygonum Cuspidatum, which grows in Asia, contain higher percentages of this component.

Resveratrol's fame stems from the "French paradox" which is a term used to describe the observation that even though the traditional French diet is high in saturated fat, the French have a low incidence of cardiovascular disease compared to other countries with similar diets.
It has been speculated that this could be due to other components that are part of the French diet, such as the resveratrol present in red wine.

Resveratrol has an antioxidant action, like all polyphenols.
This can neutralize free radicals and reduce oxidative stress in cells.

It can help eliminate menopausal symptoms.
Resveratrol has also been reported to act as an activator of sirtuins, genes that are activated during calorie restriction.

The pomegranate is a fruit that since ancient times has been used as a food and as an alternative medicine to reduce infections.
Pomegranate extract is a powerful antioxidant and its antioxidant value is higher than red wine and green tea, thanks to its high content of ellagitannins and anthocyanins.

Pomegranate is currently being investigated as a potential ally to synthesize collagen and its possible effectiveness in reducing joint pain and can help protect and repair the skin.

The protein extract is obtained from homogenized pig kidneys through a combination of salt precipitation and high-speed spinning.

The obtained precipitate essentially contains proteins with 7 % of the enzyme diamine oxidase (number 1.4.3.22 of the CE nomenclature of enzymes) and is re-suspended in a physiological buffer system.

The obtained pig kidney extract is formulated in the form of enteric-coated encapsulated pellets or enteric-coated tablets to reach the active sites of digestion.

PQQ, or pyrroloquinoline quinone, is a cofactor and natural compound found in some foods, such as tofu, parsley, and green tea.
It is known for its antioxidant and anti-inflammatory properties and has been researched for its potential health effects.
It is a molecule associated with different biological processes such as reproduction, growth, aging and mitochondrial biogenesis.
According to recent studies, it can help increase the number of mitochondria in cells.

Specifically, Active Revive Celular contains PQQ of a registered trademark, MGCPQQ.®

MGCPQQ® is a naturally occurring pure source of pyrroloquinoline quinone (PQQ) disodium salt, which is naturally found in small amounts in plants and meats.
MGCPQQ® is a water-soluble, reddish-brown powder that is harvested using Mitsubishi Gas Chemical's proprietary fermentation process.
The ingredient is registered on the European Union's list of new food ingredients.

MGCPQQ® has been studied in dozens of in vitro and in vivo clinical trials.
Mitsubishi Gas Chemical's proprietary fermentation process for harvesting MGCPQQ® naturally is well-controlled and well-documented and certified as safe.

PureWay C® is a patented brand name vitamin C.
The advantage is that it has a larger operating area and much more effective.
PureWay C® ensures greater bioavailability and absorption and is maintained more effectively in human cells than other sources of vitamin C.

PureWay C® contains:

• Vitamin C: as ascorbic acid from citrus fruits (orange, lemon, lime and tangerine).
• Lipid metabolites: from plant sources.
  In PureWay-C® they act as transporters of vitamin C, to increase its intestinal absorption and tissue distribution, entering the cells faster, safer and more effectively.
• Citrus bioflavonoids: from species of the Citrus genus (orange, lemon, lime and mandarin), among which are: rutin, naringin, hesperidin, neohesperidin, naringenin, hesperitin and nomiline.
  These bioflavonoids are added in trace amounts as preservatives in the formula.

Vitamin C is a water-soluble antioxidant with a high reducing power.
It acts as a cofactor for numerous enzymes involved in the biosynthesis of collagen, carnitine and some neurotransmitters, and can trap a wide variety of reactive oxygen and nitrogen species in aqueous media.
Vitamin C is considered essential, as it cannot be synthesized by humans.

This vitamin is mainly found in foods of plant origin in which it appears naturally in two interconvertible chemical forms: ascorbic acid (reduced form) and dehydroascorbic acid (oxidized form); Both forms have similar biological action.
In general, all fruits and vegetables contain it in greater or lesser amounts.
The richest fruits are acidic, since low pH stabilizes vitamin C (kiwi, strawberries, currants, mango, orange).

Among its functions, vitamin C contributes:

• the normal functioning of the immune system during and after intense physical exercise.
• to the normal formation of collagen for the normal functioning of blood vessels.
• to the normal formation of collagen for normal bone function.
• to the normal formation of collagen for the normal functioning of cartilage.
• to the normal formation of collagen for the normal functioning of the gums.
• to the normal formation of collagen for the normal functioning of the skin.
• to the normal formation of collagen for the normal functioning of the teeth.
• to normal energy metabolism.
• to the normal functioning of the nervous system.
• to normal psychological function.
• to the normal functioning of the immune system.
• to the protection of cells against oxidative damage.
• Help reduce tiredness and fatigue.
• to regenerate the reduced form of vitamin E.
• improve iron absorption.

Quatrefolic® is a fourth-generation folate.
It is a registered trademark of Vitamin B9, (also known as Folate).
It is the glucosamine salt of (6S)-5-methyltetrahydrofolate (5-MTHF) and is structurally identical to the reduced, active form of folate found in our bodies. It is an innovative dietary ingredient that provides greater stability, improved bioavailability, higher water solubility, and flexibility for multi-ingredient formulations compared to a third-generation 5-MTHF calcium salt. In recent years, more and more evidence has been found of the advantages of reduced folate over folic acid.
The use of reduced folate (particularly reduced and methylated as Quatrefolic®) is the solution since a large part of the world's population cannot assimilate and metabolize folic acid from foods or food supplements. Quatrefolic® is manufactured under controlled conditions according to cGMP and since glucosamine does not come from animals or shellfish, Quatrefolic® is a great choice for vegetarians.
In addition, Quatrefolic® is considered safe and is recognized as GRAS.
Vitamin B9, also called folate, is one of the water-soluble B vitamins.
Its name comes from the word "folia" which means leaf in Latin, due to its natural presence in green leafy vegetables.
Also in beans, wheat germ and yeast.
Other sources include egg yolk, milk and dairy, beetroot, orange juice, and wholemeal bread.
Vitamin B9 is given in different forms: the natural one which is folate and folic acid, which is a synthetic folate compound used in vitamin supplements and fortified foods because it is more stable. Folic acid contributes:

• to the growth of maternal tissues during pregnancy.
• to normal amino acid synthesis.
• to the normal formation of blood cells.
• to normal homocysteine metabolism.
• to normal psychological function.
• to the normal functioning of the immune system.
• Helps to reduce tiredness and fatigue.
• to the process of cell division.

In food supplements, folate is usually found in the form of folic acid, but different salts such as 5-MTHF (methylfolate) can also be used.
Quatrefolic® glucosamine salt (6S)-5-methyltetrahydrofolate (5-MTHF).
The source of folic that is selected is very important.
Dietary supplements containing 5-MTHF may be better than folic acid for some people who have a gene mutation called MTHFR C677T because their bodies can use this form more easily.
This is because the body cannot transform the synthetic folic or folic present in fruits and vegetables into its methylated active form.
That is why our formulas contain Quatrefolic® (5-MTHF).

Quercetin is a flavonoid found in a wide variety of foods, including fruits and vegetables such as apples, onions, berries, broccoli, and spinach.
It is the most abundant flavonoid and the most common in the human diet.
For example, if we ate 100 g of raw red onion a day we would be taking about 78 mg of quercetin.