Memory

Active
National Code: 185516.9

60 capsules

Dietary supplement based on plants such as, Bacopa monnieri and Ginkgo biloba, B vitamins and antioxidants that promote cognitive function.

Product Features

Memory
Vegan
Memory
Gluten free
Memory
Lactose free

Product benefits

Memory
Homocysteine control
Energy
Nervous system
Omega 3

Product Features

Memory
Vegan
Memory
Gluten free
Memory
Lactose free

Main assets ofMemory

Memophenol™ (Polyphenols)

Memophenol™ is a mixture of flavonols and stilbenes from grapes and anthocyanins present in wild blueberries.

Longlife® (Curcumin)

(Curcuma longa)
Longvida® is a patented curcumin extract that acts directly on target tissues and the brain.

Dry extract of Bacopa monnieri

(Bacopa monnieri (L.) Pennell)
It can help improve concentration and memory and maintain good cognitive function.

Hill

(Choline Bitartrate)
Essential for producing acetylcholine, a neutrotransmitter so it plays an important role in memory.

Ginkgo dry extract

(Ginkgo biloba L.)
Supports cognitive function.

Dry extract of Masson Pine

(Pinus massoniana Lamb.)
Pine extract rich in antioxidants (PACs) that can be beneficial in neuroprotection.

Vitamin B6 or Pyridoxine

(Pyridoxine HCL)
Contributes to the normal metabolism of homocysteine and the normal functioning of the nervous system.

Vitamin B12 or Methylcobalamin

(Methylcobalamin)
Contributes to the normal metabolism of homocysteine and the normal functioning of the nervous system.
Memory
Memophenol™ (Polyphenols)

Memophenol™ is a mixture of flavonols and stilbenes from grapes and anthocyanins present in wild blueberries. Clinical studies have shown that the synergistic association of these polyphenols favors plasticity and brain microcirculation, as well as helping to reduce oxidative stress, one of the causes of brain aging. Memophenol™ is a proprietary formula rich in essential polyphenols to improve cognitive performance and memory.
It combines two noble fruit extracts, the best sources of bioavailable polyphenols for synergistic activity:

  • The Champagne grape (Vitis vinifera L.), 5 times richer in monomers than other grape species. These are small polyphenols that can be assimilated more easily by the body.
  • Canadian blueberries (Vaccinium), which contain active molecules that are complementary to those in grapes, making it more effective.

The formula combines these two extracts to have a synergistic action on neuroprotection.
Memophenol provides the best source of scientifically proven essential polyphenols to support cognition with demonstrated bioavailability. Memophenol™, twice patented and backed by science and claims, is a highly polyphenol-rich formula clinically proven to improve learning and memory.

Kesse-Guyot et al., 2012; Devore et al., 2012; Letenneur et al., 2007; Krikorian et al., 2010, 2012

Impellizzeri D, Tomasello M, Cordaro M, D’Amico R, Fusco R, Abdelhameed AS, Wenzel U, Siracusa R, Calabrese V, Cuzzocrea S, Di Paola R. MemophenolTM Prevents Amyloid-β Deposition and Attenuates Inflammation and Oxidative Stress in the Brain of an Alzheimer’s Disease Rat. Int J Mol Sci. 2023 Apr 8;24(8):6938. doi: 10.3390/ijms24086938. PMID: 37108102; PMCID: PMC10138369.

Lopresti AL, Smith SJ, Pouchieu C, Pourtau L, Gaudout D, Pallet V, Drummond PD. Effects of a polyphenol-rich grape and blueberry extract (Memophenol™) on cognitive function in older adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study. Front Psychol. 2023 Mar 29;14:1144231. doi: 10.3389/fpsyg.2023.1144231. PMID: 37063535; PMCID: PMC10095830.

Bensalem J, Dudonné S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, Dubreuil S, Paradis ME, Pomerleau S, Capuron L, Hudon C, Layé S, Desjardins Y, Pallet V. Polyphenols From Grape and Blueberry Improve Episodic Memory in Healthy Elderly with Lower Level of Memory Performance: A Bicentric Double-Blind, Randomized, Placebo-Controlled Clinical Study. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):996-1007. doi: 10.1093/gerona/gly166. PMID: 30032176.

Bensalem, Julien & dal-pan, Alexandre & Gillard, Elodie & Calon, Frédéric & Pallet, Veronique. (2015). Protective effects of berry polyphenols against age-related cognitive impairment. Nutrition and Aging. Preprint. pp. 1-18. 10.3233/NUA-150051.

Bensalem J, Servant L, Alfos S, et al. Dietary Polyphenol Supplementation Prevents Alterations of Spatial Navigation in Middle-Aged Mice. Frontiers in Behavioral Neuroscience 2016; 10: 9.

Dal-Pan A, Dudonne S, Bourassa P, et al. Cognitive-Enhancing Effects of a Polyphenols-Rich Extract from Fruits without Changes in Neuropathology in an Animal Model of Alzheimer’s Disease. Journal of Alzheimer’s disease : JAD 2016.

Kesse-Guyot E, Fezeu L, Andreeva VA, et al. Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later. The Journal of nutrition 2012; 142(1): 76-83.

Devore EE, Kang JH, Breteler MMB, Grodstein F. Dietary intakes of berries and flavonoids in relation to cognitive decline. Annals of neurology 2012; 72(1): 135-43.

Krikorian R, Shidler M, Nash T, et al. Blueberry supplementation improves memory in older adults. J Agric Food Chem 2010; 58(7): 3996-4000.

Krikorian R, Boespflug EL, Fleck DE, et al. Concord grape juice supplementation and neurocognitive function in human aging. J Agric Food Chem 2012; 60(23): 5736-42.

Letenneur L, Proust-Lima C, Le Gouge A, Dartigues JF, Barberger-Gateau P. Flavonoid intake and cognitive decline over a 10-year period. American journal of epidemiology 2007; 165(12): 1364-71.

Dudonné, Stéphanie & Dal-Pan, Alexandre & Dubé, Pascal & Varin, Thibault & Calon, Frédéric & Desjardins, Yves. (2016). Potentiation of the bioavailability of blueberry phenolic compounds by co-ingested grape phenolic compounds in mice, revealed by targeted metabolomic profiling in plasma and feces. Food Funct.. 7. 10.1039/C6FO00902F.

Longlife® (Curcumin)

Longvida® is a standardized proprietary curcumin extract that provides free curcumin to target tissues and the brain.
Statistically significant clinical results have been obtained in the improvement of the functions of the cognitive system and mood. Curcumin, the main source of curcuminoids from the spice turmeric, has gained increasing global recognition for its multiple health benefits, particularly its antioxidant and anti-inflammatory properties.
As a result, the ingredient is used as a means to support health and longevity. Specifically turmeric (Curcuma longa):

  • It prevents the accumulation of fats and facilitates their elimination by the liver.
  • Helps maintain liver health.
  • Helps maintain the health of the lungs and upper respiratory tract.
  • Helps maintain the effectiveness of the immune system.
  • Helps maintain allergy resistance.
  • Antioxidant / Protects from free radicals.
  • Supports nervous system function.
  • Supports heart function.
  • Supports blood circulation.
  • Helps keep skin healthy.
  • It is used to stimulate appetite.
  • Helps promote appetite in cases of appetite loss.

Longvida® is a safe, effective, and clinically supported curcumin extract.
It follows the global regulatory compliance framework, offering superior quality assurance and control parameters, as well as being supported by rigorous traceability and sustainability initiatives and clinical testing.
Longvida® allows for the absorption of free curcumin into the blood and target tissues.
This allows Longvida’s curcumin to cross the blood-brain barrier and deliver effective free curcumin in easy-to-administer daily doses, making it Cognitive Curcumin of Choice®.

DiSilvestro RA, Joseph E, Zhao S, Bomser J. Diverse effects of a low dose supplement of lipidated curcumin (as Longvida®) in healthy middle aged people. Nutr J. 2012 Sep 26;11:79. doi: 10.1186/1475-2891-11-79. PMID: 23013352; PMCID: PMC3518252.

Efficacy of Longvida® in Humans with Neurological Disorders: The LONG -12 Study. Submitted for publication, Advances in Pharmacology.

Binding of Curcumin to Amyloid-beta from a Single-dose of Lipidated Curcumin (Longvida®) in Humans: Multicenter Clinical Trial. Los Angeles. CA

Acute human bioavailability of Longvida®: 65x Greater Bioavailability.Gota et al.J Ag Food Chem 2010 58(4): 2095 – 2099.

Cox KH, Pipingas A, Scholey AB. Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. 2015 May;29(5):642-51. doi: 10.1177/0269881114552744. Epub 2014 Oct 2. PMID: 25277322.

“Scholey A: Preservation or enhancement of working memory may aid in preventing or reversing age -related memory impairments or dementia risk. Ability to sustain focus on any task is essential to its successful completion, and improvements to sustained attention could have wide -reaching benefits. Cox et al. J Psychopharmacol,
029881114552744. First Published on 2 Oct 2014.”

Hu S, Maiti P, Ma Q, Zuo X, Jones MR, Cole GM, Frautschy SA. Clinical development of curcumin (as Longvida®) in neurodegenerative disease. Expert Rev Neurother. 2015 Jun;15(6):629-37. doi: 10.1586/14737175.2015.1044981. PMID: 26035622; PMCID: PMC6800094.

Rangel A et al. The GFAP-IL6 mouse, a model of chronic neuroinflammation with deficits in motor coordination and memory – rescue by curcumin. 2015. Keystone Symposia Meetings. Neuroinflammation in Diseases of the Central Nervous System. Taos, New Mexico, USA.

Nahar PP, Slitt AL, Seeram NP. Anti-Inflammatory Effects of Novel Standardized Solid Lipid Curcumin (as Longvida®) Formulations. J Med Food. 2015 Jul;18(7):786-92. doi: 10.1089/jmf.2014.0053. Epub 2014 Dec 9. PMID: 25490740; PMCID: PMC4492550.

Gupte PA, Giramkar SA, Harke SM, Kulkarni SK, Deshmukh AP, Hingorani LL, Mahajan MP, Bhalerao SS. Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. J Inflamm Res. 2019 Jun 5;12:145-152. doi: 10.2147/JIR.S205390. PMID: 31239749; PMCID: PMC6559772.

Santos-Parker JR, Lubieniecki KL, Rossman MJ, Van Ark HJ, Bassett CJ, Strahler TR, Chonchol MB, Justice JN, Seals DR. Curcumin supplementation and motor-cognitive function in healthy middle-aged and older adults. Nutr Healthy Aging. 2018 Jun 15;4(4):323-333. doi: 10.3233/NHA-170029. PMID: 29951592; PMCID: PMC6004902.

Phipps KR, Bali V, Kukadia D, Patel C, Muchhara J. Safety assessment of a solid lipid curcumin particle preparation: In vitro and in vivo genotoxicity studies. J Appl Toxicol. 2023 Jun;43(6):929-939. doi: 10.1002/jat.4434. Epub 2023 Jan 15. PMID: 36609910.

Hazarey VK, Sakrikar AR, Ganvir SM. Efficacy of curcumin in the treatment for oral submucous fibrosis – A randomized clinical trial. J Oral Maxillofac Pathol. 2015 May-Aug;19(2):145-52. doi: 10.4103/0973-029X.164524. PMID: 26604488; PMCID: PMC4611920.

Santos-Parker JR, Strahler TR, Bassett CJ, Bispham NZ, Chonchol MB, Seals DR. Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress. Aging (Albany NY). 2017 Jan 3;9(1):187-208. doi: 10.18632/aging.101149. PMID: 28070018; PMCID: PMC5310664.

Dry extract of Bacopa monnieri

Bacopa monnieri is a nootropic herb that has been traditionally used in medicine to improve longevity and cognitive status.
It has also been shown to improve age-related cognitive decline (particularly in the process of speed and memory).

  • It can help improve concentration and memory.
  • Helps maintain good cognitive function
  • It helps maintain memory with declining age and preserve cognitive function.
  • Helps peripheral blood microcirculation
  • It contributes to normal blood circulation, which is associated with brain performance.
Hill

Choline is an essential nutrient that belongs to the group of B vitamins. It is not a vitamin as it can be synthesized in small amounts in the liver.
Most of the choline found in the body comes from the food you eat.
Among its sources, it can be obtained from meat, eggs and dairy products.
It is also obtained from cruciferous vegetables such as Brussels sprouts, broccoli and cauliflower and some types of beans, nuts, seeds and whole grains. On the other hand, choline is very important for cell membranes and for producing acetylcholine, a neutrotransmitter.
Therefore, it plays an important role in memory and muscle control.

Among its functions, the hill contributes:

  • to normal homocysteine metabolism.
  • to normal lipid metabolism.
  • to maintain normal liver function.

Recent studies suggest that, in addition to the properties of choline for the proper functioning of organs such as the liver or brain, it can contribute to maintaining the muscular system and reducing cardiovascular risk.

Ginkgo dry extract

Ginkgo biloba extract is obtained from the leaves of the Ginkgo tree.
The most beneficial components of ginkgo are thought to be flavonoids, which have powerful antioxidant qualities, and terpenoids, which help improve circulation by dilating blood vessels. Ginkgo biloba supports cognitive function.
Active Memory contains 150 mg of Ginkgo biloba of which 36 mg are flavonol glycosides (flavonoids) and 9 mg of terpene lactones (terpenoids)

Dry extract of Masson Pine

The Pinus Masoniana is a conifer native to Taiwan.
Pine bark contains natural substances called oligomeric proanthocyanidins (PACs), which are a class of antioxidants that give pine bark its color.
The dry extract of the bark is used worldwide for its antioxidant and anti-inflammatory properties, as well as its health benefits. The role of antioxidants in Masson pine extract may contribute to neuroprotective activity.

Vitamin B6 or Pyridoxine

Vitamin B6 is a water-soluble vitamin.
There are three natural forms of vitamin B6: pyridoxine, pyridoxamine, and pyridoxal, and all are normally present in food, however, pyridoxine is the most well-known form. Sources of vitamin B6 (pyridoxine) are chicken, beef, especially liver, and pork.
Good sources include fish (salmon, tuna, sardines, grouper, and herring), nuts (walnuts, peanuts), bread, corn, and whole grains.
Vegetables and fruit are generally poor sources of vitamin B6. Among its functions, vitamin B6 contributes:

  • to the normal synthesis of cysteine.
  • to normal homocysteine metabolism.
  • to normal psychological function.
  • to normal energy metabolism.
  • to the normal functioning of the nervous system.
  • to normal protein and glycogen metabolism.
  • to the normal formation of red blood cells.
  • to the normal functioning of the immune system.
  • Helps to reduce tiredness and fatigue.
  • to regulate hormonal activity.
Vitamin B12 or Methylcobalamin

Vitamin B12 is the largest and most complex of the vitamins.
Vitamin B12 comprises the only cobalt-containing molecules (called cobalamins) with biological activity in humans. Vitamin B12 is produced exclusively by microbial synthesis in the digestive tract of animals.
Therefore, people who follow a vegetarian or vegan diet have to provide this vitamin through food supplements. It is obtained from products with animal proteins, especially organ meats.
Other good sources include fish, eggs, and dairy products. Among its functions, vitamin B12 contributes:

  • to normal homocysteine metabolism.
  • to normal energy metabolism.
  • to the normal functioning of the nervous system.
  • to normal psychological function.
  • to the normal formation of red blood cells.
  • to the normal functioning of the immune system.
  • Helps to reduce tiredness and fatigue.
  • to the process of cell division.

Product Description

Nutritional information

Description

Main causes of memory loss and how diet can help Age, hormonal drop, mainly estrogen in women, and a diet high in saturated fats and sugars are the main factors that contribute to cognitive decline.
On the other hand, a diet rich in omega 3 or polyunsaturated oils from oily fish, as well as the polyphenols of berries, and red fruits, poop, spices and foods rich in vitamins B9 (folates), B12, B6 are the type of foods that can provide the necessary nutrients for brain health.
These B vitamins contribute to the maintenance of homocysteine levels in the blood.

How to take Memory

3 capsules a day.
Take 1 capsule a day before each main meal.

Presentation

60 capsules

Indications

  • Supports cognitive function.

Ingredients

Memophenol™(Dry extract of grape (Vitis vinifera L., fruit) and wild blueberry (Vaccinium angustifolium A., fruit) 29% avonoids and 0.05% resveratrol), Longvida® [(optimized dry extract of turmeric (Curcuma longa L., rhizome 23% curcuminoids), soy lecithin], vegetable [agente de recubrimiento (hidroxipropilmetilcelulosa)]capsule, dry extract of Bacopa (Bacopa monnieri (L.)
Pennell, herb, 40% bacosides), choline bitartrate, bulking agent (dicalcium phosphate), dry extract Ginkgo (Ginkgo biloba L., leaves 24% flavonol glycosides and 6% terpene lactones), dry extract of Masson’s pine [Pinnus massoniana Lamb., bark, 95% proanthocyanidins (PAC)], anti-caking agents (magnesium stearate and silicon dioxide), Vitamin B6 (pyridoxal-5′-phosphate), Quatrefolic® (vitamin B9 (folic acid ((6S)-5-methyltetrahydrofolic acid, salt glucosamine))] and Vitamin B12 (methylcobalamin).

Contraindications / Allergens

If you are taking blood thinners or antiplatelet agents, consult your doctor before taking the product.

Warnings

Food supplements should not be used as substitutes for a varied and balanced diet or a healthy lifestyle.
Do not exceed the recommended daily dose.
Keep out of reach of young children. If you are taking blood thinners or antiplatelet agents, consult your doctor before taking this product.
The product is not recommended for use in children, or during pregnancy and breastfeeding.

Memory
Vegan
Memory
Gluten free
Memory
Lactose free
Nutritional Information
IngredientsDaily Dose%NRV
Memophenol™(Dry Grape Extract (Vitis vinifera L, fruit) and Wild Blueberry (Vaccinium angustifolium A)450 mg
- Flavonoids130.50 mg
- Resveratrol0.225 mg
Longvida® Turmeric Dry Extract (Curcuma longa)400 mg
- Curcuminoids92 mg
Ext.
Bacopa (Bacopa monnieri (L.)
Pennell)
300 mg
-Bacosides120 mg
Choline Bitartrate300 mg
Ext.
dried Ginkgo (Ginkgo biloba L.)
150 mg
- Flavonol glycosides36 mg
- Terpene lactones9 mg
Ext.
dried Masson Pine (Pinus massoniana Lamb.)
120 mg
-PAC114 mg
Vitamin B6 (pyridoxal-5'-phosphate)1.05  mg75%
Vitamin B9 (5-methyltetrahydrofolate) Quatrefolic®300  μg150%
Vitamin B12 (Methylcobalamin)1.875  μg75%

NRV: Nutrient Reference Value.
*%NRV not defined.

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