B-Complex

Active Omega 3
National Code: 212916.0

60 pearls

Dietary supplement rich in Omega-3 fatty acids (DHA in the form of triglycerides) and B complex vitamins that contribute to the reduction of tiredness and fatigue and the normal functioning of the immune system.

Product Features

B-Complex
Contains fish
B-Complex
Gluten free
B-Complex
Lactose free

Product benefits

Energy
Immunity
Nervous system
Memory
Omega 3

Product Features

B-Complex
Contains fish
B-Complex
Gluten free
B-Complex
Lactose free

Main assets ofB-Complex

Omega 3

Each pearl contains 1000 mg of fish oil, of which 760 mg is DHA (docosahexaenoic acid).

DHA

(Docosahexaenoic acid)
Docosahexaenoic acid (DHA) contributes to maintaining the normal functioning of the brain and contributes to the maintenance of vision under normal conditions.

Vitamin B3 or Niacin

(Niacina)
Contributes to the normal functioning of the nervous system.

Vitamin B1 or Thiamine

(Thiamine HCL)
Contributes to the normal functioning of the nervous system.

Vitamin B2 or Riboflavin

(Riboflavin)
Contributes to the normal functioning of the nervous system.

Vitamin B12 or Methylcobalamin

(Methylcobalamin)
Contributes to the normal functioning of the nervous system.

Quatrefolic® (Vitamin B9 or Folate or Folic Acid)

(5-methyltetrahydrofolate)
Contributes to normal psychological function.

Vitamin B8 or Biotin

(Biotin)
Contributes to the normal functioning of the nervous system.
Stress Control
Omega 3

Each pearl contains 1000 mg of fish oil, of which 760 mg is DHA (docosahexaenoic acid).
Omega-3 fatty acids from cold-extracted fish oil contain 76% DHA in the form of triglycerides to promote absorption. Omega 3 are a type of essential fatty acids that cannot be synthesized by the body and therefore must be incorporated through the diet.
To meet the daily needs of this nutrient, it is often necessary to resort to the consumption of food supplements, especially in stages when these requirements increase, such as pregnancy(1). Long-chain polyunsaturated fatty acids (EPA and DHA) are primarily produced from marine microalgae before entering the fish food chain.
These microalgae have the enzymes necessary to efficiently synthesize DHA, from the fatty acid α-linolenic acid (ALA).
However, the ALA (precursor of EPA and DHA) obtained from the diet produces little DHA in the human body, so to obtain DHA it is more effective to consume oily fish or take a dietary supplement of Omega 3 fatty acids(2). Omega-3s are mostly found in oily fish such as salmon, mackerel, tuna, herring and sardines.
They are also found in nuts and seeds (such as flaxseed, chia seeds, and black walnuts).
This fish oil has the SLTEX seal, a seal of the Solutex GC company that guarantees the highest criteria of purity and quality when obtaining specialties aimed at human consumption; through the use of a unique supercritical CO2 extraction and purification fluid technology.
It also guarantees Omega 3, both EPA and DHA, in very high purity and concentration.
The high concentration of EPA and DHA means greater absorption and incorporation by our body.

1 B. Koletzko, I. Cetin, J.T. Brenna. Dietary fat intakes for pregnant and lactating women. Br J Nutr, 98 (2007), pp. 873-877.

2 J.R. Hibbeln, L.R. Nieminen, T.L. Blasbalg, J.A. Riggs, W.E. Lands. Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity. Am J Clin Nutr, 83 (2006), pp. 1483S-1493S

DHA

Docosahexaenoic acid (DHA) is an omega-3 fatty acid with anti-inflammatory properties and an important role in brain and vision development.
Omega 3 is essential for the body and is obtained through food.
They are mostly found in oily fish such as salmon, mackerel, tuna, herring and sardines.
Also in nuts and seeds (such as flaxseed, chia seeds and black walnuts). Specifically, DHA is important for maintaining membrane fluidity, an essential property to enable the activity of excitable cells such as neurons.
In the retina, DHA accumulates mainly in the membrane and this fatty acid actively participates in the process of transformation of the light stimulus.
But the greatest importance of DHA has been studied particularly in the brain.
The brain is an organ composed of 60% phospholipids, of which more than half of that percentage is DHA.
It is suggested that it positively influences the functioning of the nervous system and brain. Docosahexaenoic acid (DHA) contributes:

  • to maintain normal brain function.
  • to the maintenance of vision under normal conditions.

The beneficial effect is obtained with an intake of 250 mg of DHA.

  Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) contribute:

  • to the normal functioning of the heart.
Vitamin B3 or Niacin

Vitamin B3, also called niacin, is one of eight water-soluble B vitamins.
The term niacin refers to ‘nicotinic acid’ and ‘nicotinamide’ (also called niacinamide).
Both are used to form coenzymes. Yeast, liver, poultry and lean meat, nuts, and legumes are the main sources of niacin obtained through food. Among the functions, niacin contributes:

  • to the normal functioning of the nervous system.
  • to normal psychological function.
  • Helps to reduce tiredness and fatigue.
  • to normal energy metabolism.
  • to the maintenance of mucous membranes under normal conditions.
  • to the maintenance of the skin in normal conditions.

Vitamin B1 or Thiamine

Vitamin B1, also called thiamine, is one of eight water-soluble B vitamins.
Vitamin B1 (thiamine) is present in most foods, but usually in small amounts.
The best source of thiamine is dry brewer’s yeast.
Other good sources include meat (especially pork), some types of fish (eel, tuna), wholemeal cereals and bread, nuts, fresh and dried legumes, and potatoes. Among the functions, vitamin B1 contributes:

  • to the normal functioning of the nervous system.
  • to normal energy metabolism.
  • to normal psychological function.
  • to the normal functioning of the heart.
Vitamin B2 or Riboflavin

Vitamin B2, also called riboflavin, is one of the most widespread water-soluble vitamins. The most important and common dietary sources are milk and dairy products, lean meat, eggs, and leafy greens.
Yeast and liver have the highest concentrations, but they don’t have much relevance in today’s nutrition. Among its functions, vitamin B2 contributes:

  • to the normal functioning of the nervous system.
  • Helps to reduce tiredness and fatigue.
  • to normal energy metabolism.
  • to the maintenance of mucous membranes under normal conditions.
  • to the maintenance of red blood cells under normal conditions.
  • to the maintenance of the skin in normal conditions.
  • to the maintenance of vision under normal conditions.
  • to normal iron metabolism.
  • to the protection of cells against oxidative damage.

Vitamin B12 or Methylcobalamin

Vitamin B12 is the largest and most complex of the vitamins.
Vitamin B12 comprises the only cobalt-containing molecules (called cobalamins) with biological activity in humans. Vitamin B12 is produced exclusively by microbial synthesis in the digestive tract of animals.
Therefore, people who follow a vegetarian or vegan diet have to provide this vitamin through food supplements. It is obtained from products with animal proteins, especially organ meats.
Other good sources include fish, eggs, and dairy products.

Among its functions, vitamin B12 contributes:

  • to the normal functioning of the immune system.
  • Helps to reduce tiredness and fatigue.
  • to the normal functioning of the nervous system.
  • to normal psychological function.
  • to normal energy metabolism.
  • to normal homocysteine metabolism.
  • to the normal formation of red blood cells.
  • to the process of cell division.
Quatrefolic® (Vitamin B9 or Folate or Folic Acid)

Vitamin B9, also called folate, is one of the water-soluble B vitamins.
Its name comes from the word “folia” which means leaf in Latin, due to its natural presence in green leafy vegetables.
Also in beans, wheat germ and yeast.
Other sources include egg yolk, milk and dairy, beetroot, orange juice, and wholemeal bread.
Vitamin B9 is given in different forms: the natural one which is folate and folic acid, which is a synthetic folate compound used in vitamin supplements and fortified foods because it is more stable. Folic acid contributes:

  • to normal psychological function.
  • Helps to reduce tiredness and fatigue.
  • to the growth of maternal tissues during pregnancy.
  • to normal amino acid synthesis.
  • to the normal formation of blood cells.
  • to normal homocysteine metabolism.
  • to the normal functioning of the immune system.
  • to the process of cell division.

Tiredness and fatigue associated with stress can be a causative factor in hair loss.
In food supplements, folate is usually found in the form of folic acid, but different salts such as 5-MTHF (methylfolate) can also be used.
Quatrefolic® glucosamine salt (6S)-5-methyltetrahydrofolate (5-MTHF).
The source of folic that is selected is very important.
Dietary supplements containing 5-MTHF may be better than folic acid for some people who have a gene mutation called MTHFR C677T because their bodies can use this form more easily.
This is because the body cannot transform the synthetic folic or folic present in fruits and vegetables into its methylated active form.
That is why our formulas contain Quatrefolic® (5-MTHF).
Quatrefolic® is a fourth-generation folate.
It is a registered trademark of Vitamin B9, (also known as Folate).
It is the glucosamine salt of (6S)-5-methyltetrahydrofolate (5-MTHF) and is structurally identical to the reduced, active form of folate found in our bodies. It is an innovative dietary ingredient that provides greater stability, improved bioavailability, higher water solubility, and flexibility for multi-ingredient formulations compared to a third-generation 5-MTHF calcium salt. In recent years, more and more evidence has been found of the advantages of reduced folate over folic acid.
The use of reduced folate (particularly reduced and methylated as Quatrefolic®) is the solution since a large part of the world’s population cannot assimilate and metabolize folic acid from foods or food supplements.
Quatrefolic® is manufactured under controlled conditions according to cGMP and since glucosamine does not come from animals or shellfish, Quatrefolic ® is a great choice for vegetarians.
In addition, Quatrefolic® is considered safe and is recognized as GRAS.

1. Patanwala I et al. Folic acid handling by the human gut: implications for food fortification and supplementation. Am J Clin Nutr. 2014

2. Scaglione F, Panzavolta G. Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica. 2014

3. Ulrich CM, Potter JD. Folate supplementation: too much of a good thing? Cancer Epidemiol Biomarkers Prev. 2006

4. Pietrzik K et al. Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin Pharmacokinet. 2010

5. Lawrence, Kripalani et al. « Profiling National Mandatory Folic Acid Fortification Policy Around the World. » New York: Springer; 2012

6. Ulric et al. « Folate Supplementation: Too Much of a Good Thing? » Cancer Epidemiol Biomarkers Prev 2006;15:189-193

7. Strum et al. « Enzymatic reduction and methylation of folate following pH-dependant, carrier-mediated transport in rat jejunum. » Biochim Biophys Acta 1979; 554, 249-257

8. Kelly et al. « Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements. » Am J Clin Nutr 1997:65:1790-5

9. Jamil K. Clinical Implications of MTHFR Gene Polymorphism in Various Diseases. Biol Med. 2014

10. Wilcken B et al. Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas worldwide. J Med Genet. 2003

11. Seremak-Mrozikiewicz A et al. The significance of 1793G>A polymorphism in MTHFR gene in women with first trimester recurrent miscarriages. Neuro Endocrinol Lett. 2010

12. Tsang BL et al. Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: A systematic review and meta-analysis of trials and observational studies. Am. J. Clin. Nutr. 2015

13. Sweeney MR et al. Persistent circulating unmetabolized folic acid in a setting of liberal voluntary folic acid fortification. Implications for further mandatory fortification? BMC Public Health. 2009

14. Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr. 2007

15. Smith D. A. et al. Is folic acid good for everyone? Am J Clin Nutr. 2008

16. Colman, Green, Metz et al. « Prevention of folate deficiency by food fortification. Il. Absorption of folic acid from staple foods. » Am J Clin Nutr I 975; 28:459-64

17. Shils et al. « Modern Nutrition in Health and Disease, 9th ed ». Williams & Wilkins, Balt., 1999

18. http://www.efsa.europa.eu/it/home/publication/efsafolicacid.pdf

19. Morris MS et al. « Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors ». Am J Clin Nutr. 2010

Vitamin B8 or Biotin

Vitamin B8, also known as biotin or vitamin H, is water-soluble.
There are eight different forms of biotin, but only biotin D is naturally present and possesses full vitamin activity.
Biotin can only be synthesized by bacteria, molds, yeasts, algae, and certain plant species. Biotin contributes:

  • to the normal functioning of the nervous system.
  • to normal energy metabolism.
  • to normal macronutrient metabolism.
  • to normal psychological function.
  • to the maintenance of hair in normal conditions.
  • to the maintenance of mucous membranes under normal conditions.
  • to the maintenance of the skin in normal conditions.

Product Description

Nutritional information

Description

Foods That Can Help Improve B Vitamin Levels B vitamins are a group of 8 water-soluble vitamins.
The body does not store them, so they need to be replenished daily.
B vitamins are found in animal proteins, dairy products, leafy greens, and legumes.
The importance of B vitamins begins early in the human life cycle and continues throughout their different stages of life, starting from fertility and pregnancy to adulthood and senility.
In general, its function can be divided into metabolism that leads to energy production, and anabolic metabolism, which results in bioactive molecules.
They are critical cofactors for transport between neurons and in the synthesis of neurotransmitters and many cellular metabolic pathways.
B vitamins are cofactors for many enzymes.
Reductions in food intake and absorption efficiency in some populations may warrant attention to their dietary levels of vitamin B. Most B vitamins are generally safe even if you exceed the RDIs (Recommended Daily Intake) with either fortified foods or supplements.

How to take B-Complex

1 pearl a day, with one of the main meals.

Presentation

60 pearls

Indications

  • Normal maintenance of the brain, vision and the reduction of tiredness and fatigue.
  • Normal functioning of the immune system.
  • Normal functioning of the nervous system and psychological function.
  • Normal intellectual performance.

Ingredients

Fish oil in the form of triglycerides, Omega 3 800 mg (760 DHA), Pearl (Glazing agent: fish gelatin, humectant: vegetable glycerin, water; Dyes: black iron oxide, red iron oxide); Vitamin B3 (nicotinamide); Thickener (beeswax); Vitamin B1 (thiamine HCL); water; Vitamin B2 (riboflavin), Vitamin B5 (calcium pantothenate), Vitamin B6 (pyridoxine), Antioxidant (D-alpha-tocopherol), Vitamin B12 (methylcobalamin), Vitamin B9 Quatrefolic® (L-methylfolate), D-Biotin.

Contraindications / Allergens

Contains fish.

Warnings

Dietary supplements should not be used as substitutes for a varied and balanced diet or a healthy lifestyle.
Do not exceed the expressly recommended daily dose.
Keep out of reach of young children.

B-Complex
Contains fish
B-Complex
Gluten free
B-Complex
Lactose free
Nutritional Information
IngredientsDaily Dose%NRV
Omega-3 of which:800 mg 
- DHA (docosahexaenoic acid)760mg
Vitamin B3  (niacin) - (nicotinamide)50 mg313%
Vitamin B1  (thiamine HCL)25 mg2.272%
Vitamin B2  (riboflavin)25 mg1.785%
Vitamin B5  (pantothenic acid)18 mg300%
Vitamin B6  (pyridoxine HCL)10 mg714%
Vitamin B12  (methylcobalamin)1,000 μg40.000%
Vitamin B9 Quatrefolic® (5-methyltetrahydrofolate)400  μg200%
Vitamin B8  (biotin)450  μg900%

NRV: Nutrient Reference Value.
*%NRV not defined.

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