Are Bacopa monnieri and Ginkgo biloba the best supplements for memory?

Are Bacopa monnieri and Ginkgo biloba really the best ingredients for memory and concentration? Today we will give you a scientifically proven point of view and discover in this post the best supplements for memory and concentration, discover Active Memory.

For years, these two compounds have been the undisputed protagonists in the world of cognitive supplementation, recommended to improve information retention, mental agility and brain circulation. However, recent research has revealed that there are other ingredients that are not as popular, but with even stronger scientific backing, that may offer superior benefits in optimizing brain function.

The Role of Bacopa monnieri and Ginkgo biloba in Cognitive Function

Memory and concentration are not only matters of age, but of survival in a world that demands more and more mental speed and focus. In an era where information flows at a breakneck pace and cognitive overload is the norm, improving brain performance is not a luxury, but a necessity. Students seeking a competitive edge, professionals who need to maintain their mental acuity under pressure, and older adults who want to preserve their cognitive clarity all share the same challenge.

The problem is that most continue to resort to the same old solutions. But what if the most popular compounds weren’t really the most effective? Today we know that the key is not only in using classic compounds, but in taking advantage of innovative ingredients with more powerful mechanisms of action and improved bioavailability.

Despite the fact that ingredients such as Memophenol™ and Longvida® offer a competitive advantage in terms of scientific evidence, Bacopa monnieri and Ginkgo biloba are still compounds with important benefits for memory and concentration.

Bacopa Monnieri: An Ayurvedic Classic

Bacopa Monnieri, also known as Brahmi, is an adaptogenic plant widely used in Ayurvedic medicine for its neuroprotective, antioxidant, and anxiolytic properties. Its ancestral use in India was intended to improve memory, concentration, and resistance to mental stress. Today, science has managed to confirm many of its properties through clinical studies that demonstrate its effectiveness in optimizing cognitive performance. Its main mechanism of action is its ability to regulate levels of acetylcholine, a key neurotransmitter in memory and learning. https://doi.org/10.1016/j.jep.2013.11.008

It also possesses anxiolytic effects, which can indirectly improve concentration and mental performance. Studies have shown that bacosides, the bioactive compounds present in Bacopa monnieri, have neuroprotective effects and can improve the speed of information processing, especially in older adults.

Other studies have shown that Bacoside A, Bacoside B, Bacosaponins, Betulinic Acid, etc. are the bioactive components of Brahmi belonging to various chemical families. Every known chemical component has its important role in neuroprotection. The neuroprotective properties of Brahmi and its bioactive components include reducing ROS, neuroinflammation, inhibiting amyloid-β aggregation, and improving cognitive and learning behavior. https://doi.org/10.1016/j.abb.2019.108153

Ginkgo biloba and improving cerebral circulation

Ginkgo biloba is known for its ability to improve blood flow to the brain, which can boost oxygenation and neuronal function. Its flavonoids and terpenoids have antioxidant properties that protect brain cells from oxidative damage. https://doi.org/10.1007/s00018-003-3080-1

It has been observed that the extract of Ginkgo biloba leaf (EGb 761) is more effective for cognitive improvement than the fruit, as it contains higher concentrations of its active ingredients. The extract’s ability to scavenge free radicals produced by reactive nitrogen and oxygen species is a critical contributor to the medicinal effects of this extract. When EGb 761 is combined with other plant extracts, antioxidant capabilities are often synergistically enhanced. Promising chemical compounds that have been identified in this plant include flavonoids (quercetin, kaempferol, and isorhamnetin), terpenoids (bilobalis and ginkgolides), bioflavonoids (ginkgetine, sciadopitysine, and isoginkgetine), and organic acids (ginkgolic acid), which can affect a remarkable variety of biological processes. https://doi.org/10.1155/2022/8288818

The Memophenol™ Revolution

One of the key ingredients that sets Active Memory apart One of other supplements is Memophenol™, a proprietary formula that combines flavonols and stilbenes from the Champagne grape (Vitis vinifera L.) with anthocyanins from Canadian wild blueberries (Vaccinium). These polyphenols have been scientifically studied for their impact on neuronal plasticity and brain microcirculation, fundamental factors for the maintenance of memory and learning.

Clinical studies have shown that the synergy of the polyphenols present in Memophenol™ promotes neurogenesis and reduces oxidative stress, two essential aspects in the prevention of age-related cognitive decline. The Champagne grape used in this formula is five times richer in monomers than other grape species, which facilitates superior absorption and bioavailability. In addition, Canadian blueberries contain active molecules complementary to those of grapes, strengthening cognitive function synergistically. https://doi.org/10.3389/fpsyg.2023.1144231

What makes Memophenol™ an innovation in the world of nootropics is its ability to enhance neural transmission and long-term memory consolidation. Recent studies have confirmed its effectiveness in improving learning ability and preventing cognitive decline, making it a superior alternative to more traditional ingredients.

Longlife®: the high bioavailability curcumin for the brain

Another differentiating ingredient in Active Memory is Longvida®, a proprietary curcumin extract with a unique ability to cross the blood-brain barrier and provide free curcumin to brain tissues. Curcumin, the main polyphenol in turmeric (Curcuma longa), is widely recognized for its antioxidant and anti-inflammatory effects, which are essential in neuroprotection.

One of the biggest challenges with traditional curcumin is its low bioavailability, which limits its effectiveness in the brain. Poor solubility, low intestinal absorption, rapid metabolism, and rapid systemic elimination contribute to low overall oral bioavailability. https://doi.org/10.1016/S0731-7085(96)02024-9

Longvida® has been specifically designed to solve this problem, achieving significantly higher absorption compared to other forms of curcumin. Its impact on memory and mood has been supported by clinical studies, demonstrating improvements in cognitive function, reduced neuronal inflammation, and a lower risk of long-term cognitive decline. https://doi.org/10.1016/j.joim.2018.07.001 Curcumin has a wide range of biological activities; A large number of in vitro studies on curcumin have highlighted its antioxidant, anti-inflammatory, anticancer, antiproliferative, nephroprotective, neuroprotective, hepatoprotective, immunomodulatory, and chemopreventive effects. In addition, in vitro studies have reported that curcumin modulates multiple cell signaling pathways, downregulates cell survival gene products, upregulates p53, p21, and p27, and induces apoptosis.

Which accessories to select according to cognitive needs?

Choosing the right supplement to boost brain function will depend on the individual goals and physiological mechanisms you want to enhance. Cognitive performance is not a homogeneous concept; It involves memory, concentration, mental agility, stress resistance, and long-term neural protection. Below, we explore which ingredients have been shown to be most effective according to the specific need:

To improve memory and learning

Memory is based on synaptic plasticity and efficient neural communication. To optimize information retention and neuroplasticity, it is essential to incorporate compounds that enhance the formation of new neural connections and protect against cognitive decline.

• Phosphorus: it is a key element in the composition of the phospholipids of the neuronal membrane, it improves communication between neurons and promotes memory consolidation.
• Memophenol™: Its combination of grape and cranberry polyphenols has been shown to improve learning ability and strengthen brain synapses.
• Choline: is the precursor of acetylcholine, a neurotransmitter essential for memory and information processing.

To boost concentration and mental clarity

The ability to concentrate depends on an adequate supply of oxygen and glucose to the brain, as well as optimal neuronal transmission.

• Ginkgo biloba: increases cerebral blood flow, improving the oxygenation of neurons and promoting alertness.
• High bioavailability curcumin (Longlife®): reduces chronic inflammation of the brain and protects against oxidative damage, optimizing oxygenation and cognitive performance.
• L-theanine: it is ideal for improving concentration without generating nervousness. It modulates the action of caffeine, providing a sustained state of alertness and without side effects such as anxiety or insomnia.

To improve the composition of neuronal membranes and their fluidity

Maintaining the integrity of cell membranes is key to neuronal transmission and synaptic plasticity.

• Omega-3 (DHA/EPA in optimal proportion): DHA represents a high percentage of the brain’s structural lipids. Its consumption favors the fluidity of the membranes and facilitates communication between neurons.
• Phosphatidylserine: A phospholipid crucial in the structure of neuronal membranes that has been shown to improve cognitive function and memory in older adults.

To reduce stress and anxiety without affecting mental performance

Chronic stress impairs cognitive functions by raising cortisol levels and promoting inflammation in the brain. Regulation of the hypothalamic-pituitary-adrenal (HPA) axis is critical to preserving neuronal health.

• Ashwagandha (Withania somnifera): is an adaptogen that modulates cortisol levels, reducing anxiety and improving resistance to stress without compromising concentration.
• Magnesium L-threonate: has been shown to improve neuronal plasticity and reduce hyperexcitability of the nervous system, promoting calm and mental clarity.

For long-term cognitive protection and prevention of neurological decline

Brain aging is associated with increased oxidative stress and chronic low-grade inflammation. The incorporation of antioxidants and anti-inflammatory compounds can reduce the risk of neurodegenerative diseases.

• Polyphenols (resveratrolv, quercetin, anthocyanins): these are molecules with antioxidant and anti-inflammatory properties that protect against neuronal damage.
• Alpha-lipoic acid: acts as a universal antioxidant, protecting neuronal mitochondria and promoting energy production in brain cells.

To optimize brain energy production and neuronal metabolism

The brain, although it represents only 2% of body weight, consumes approximately 20% of the body’s total energy. Maintaining proper ATP production and optimizing glucose metabolism is essential for your performance.

• B vitamin complex (especially B3 – niacin): it is essential in the production of NAD+, a coenzyme crucial in the generation of energy and in the protection of neurons.
• Coenzyme Q10: is essential for mitochondrial function and energy production at the cellular level.
• Creatine: Although best known for its role in physical performance, recent studies have shown that it improves brain function by optimizing the availability of ATP in neurons.

The Active Memory Difference: Beyond the Conventional

While most supplements on the market focus solely on Bacopa monnieri and Ginkgo biloba as their main ingredients, Salengei’s Active Memory goes further by including Memophenol™ and Longvida®, two proprietary formulas backed by clinical trials that have been shown to be more effective in improving cognitive performance.

This combination of ingredients not only optimizes memory and concentration, but also acts on long-term neuroprotection, reducing the impact of oxidative stress and inflammation on the brain.

The Main Difference Between Active Memory and Other Supplements

The main difference between Active Memory and other supplements lies in their formulation based on bioactive synergy. Making Active Memory one of the best pills for memory and concentration. Instead of limiting itself to ingredients with moderate efficacy, it incorporates compounds that have been specifically designed to maximize the absorption and bioavailability of neuroprotective actives.

This converts Active Memory a superior option compared to other supplements that only contain traditional ingredients. You can learn more and purchase it by clicking here.

How to Leverage the Benefits of Active Memory

To take full advantage of the benefits of Active Memory, it is important to follow a proper dosage and maintain consistency in its consumption. The suggested standard dosage is 2 capsules a day, preferably with a meal, to improve the absorption of the bioactive compounds. And while short-term effects may be noticeable within a few weeks, continuous consumption for at least 3 months is recommended for long-term neuroprotective benefits.

At what time of day to take it? For those looking to improve memory and concentration, it is ideal to take it in the morning or at noon. If the goal is to reduce cognitive stress and improve rest, it can be taken in the afternoon.

Contraindications and precautions to consider

Despite the benefits of these supplements, it is essential to take into account some precautions, such as drug interactions. Ginkgo biloba may have blood-thinning effects and is not recommended in people taking medications such as warfarin or aspirin. On the other hand, Bacopa Monnieri could enhance the effect of sedative or anxiolytic drugs.

Possible side effects could be mild gastrointestinal upset, especially during the first few weeks of consumption. In high doses, Ginkgo biloba can cause dizziness or headaches due to its vasodilatory effect.

As with most of these supplements, they are not recommended for pregnant or breastfeeding women. In this special case, they should be avoided in people with bleeding disorders or who will be undergoing surgery. And don’t forget that it’s always advisable to consult with a healthcare professional before starting any supplement, especially if you have pre-existing conditions or are taking other medications.

Bacopa monnieri, Ginkgo biloba, MemophenolTM and Longvida^{®Af 9O, the best ingredients for memory and concentration}

While Bacopa monnieri and Ginkgo biloba have been widely recognized as memory supplements, scientific research has shown that there are ingredients with greater clinical evidence and efficacy in cognitive optimization. Memophenol™ and Longvida® have revolutionized the formulation of supplements for memory and concentration, offering broader and more sustainable benefits.

The synergistic combination of these ingredients in Salengei’s Active Memory provides a comprehensive approach to boosting memory, improving concentration, and protecting long-term brain health. If you’re looking for a supplement that goes beyond the conventional, Active Memory represents innovation in cognitive supplementation. It is the food supplement that contains the best pills for memory and concentration. Learn more about Active Memory.

For more information we remember a previous blog that deals with nutrients to improve memory.