{"id":5208,"date":"2022-09-14T00:00:00","date_gmt":"2022-09-14T00:00:00","guid":{"rendered":"https:\/\/salengei.com\/alzheimers-disease\/"},"modified":"2022-09-14T00:00:00","modified_gmt":"2022-09-14T00:00:00","slug":"alzheimers-disease","status":"publish","type":"post","link":"https:\/\/salengei.com\/en\/blog\/alzheimers-disease\/","title":{"rendered":"Alzheimer’s disease"},"content":{"rendered":"

World Alzheimer’s Day<\/strong> is approaching.
\nEvery September 21, a special day is commemorated to raise awareness about this disease.
\nThis day is an international campaign that highlights the problems faced by people affected by this type of dementia.
\nAn opportunity for society in general and organizations to demonstrate how we can overcome these problems and help people to live better with the disease. <\/p>\n

In this post we talk about what Alzheimer’s is and we will break down the most important points, starting from the causes and consequences, to the most promising therapeutic approaches (in a very cursory way) that science continues to investigate.<\/p>\n<\/p>\n

\n\tWhat is Alzheimer’s? <\/strong><\/h1>\n

Alzheimer’s is a type of dementia<\/strong> that causes problems with memory, thinking, and behavior.
\nSymptoms usually develop slowly and worsen over time, until they are so severe that they interfere with everyday tasks. https:\/\/www.alz.org\/alzheimer-demencia\/que-es-la-enfermedad-de-alzheimer<\/a><\/p>\n

The name of this disease is due to the German doctor Alois Alzheimer who first researched and described the pathological findings of this disease.<\/p>\n

\n

Alzheimer’s is a neurodegenerative disease<\/h4>\n<\/blockquote>\n

Alzheimer’s disease is of a neurodegenerative<\/strong> type whose specific etiopathogenesis is still unknown and in which the death of nerve cells<\/strong> occurs in certain brain regions.
\nThere is, therefore, brain atrophy, decreased brain mass and impaired production of certain neurotransmitters. <\/p>\n

Of the total cluster of proteins that may participate in the development of the disease, there is a scientific consensus based specifically on two brain proteins involved.
\nThe first of these is beta-amyloid (\u03b2A), which acts from the extracellular medium and accumulates to form plaques called senile plaques.
\nThese plaques form interneuronal junctions that interrupt neuronal function. <\/p>\n

Secondly, and acting from the intracellular environment, the accumulation of hyperphosphorylated forms of TAU protein can be observed.
\nIn this case, intraneuronal neurofibrillary tangles are formed that block the cellular transport systems. https:\/\/www.alzint.org\/u\/WorldAlzheimerReport2018.pdf<\/a><\/p>\n<\/p>\n

\n\tHow is the diagnosis suspected?<\/strong><\/h1>\n

The first symptoms of Alzheimer’s disease can be:<\/p>\n