{"id":5191,"date":"2022-01-26T00:00:00","date_gmt":"2022-01-26T00:00:00","guid":{"rendered":"https:\/\/salengei.com\/how-to-deal-with-sleep-problems\/"},"modified":"2022-01-26T00:00:00","modified_gmt":"2022-01-26T00:00:00","slug":"how-to-deal-with-sleep-problems","status":"publish","type":"post","link":"https:\/\/salengei.com\/en\/blog\/how-to-deal-with-sleep-problems\/","title":{"rendered":"How to Deal with Sleep Problems"},"content":{"rendered":"<p>Many of us constantly have or have had a sleepless night.<br \/>\nDifficulty falling asleep is a very common problem.<br \/>\nIn this post, in addition to focusing on falling asleep through the reduction of latency time, we also consider stress reduction as a necessary action to achieve this.<br \/>\nHigh levels of this disruptor (stress) are generally associated with sleep problems. <strong><a href=\"http:\/\/salengei.com\/active-sweet-dreams\">Active Sweet Dreams<\/a><\/strong> contributes to pre-dream relaxation, so important in balance to obtain a conciliatory rest.   <\/p>\n<\/p>\n<h1>\n\t<strong>Understanding a little more physiology<\/strong><\/h1>\n<p>Sleep architecture refers to the basic structural organization of normal sleep.<br \/>\nThere are two types of sleep, <strong>non-rapid eye movement (NREM) sleep<\/strong> and <strong>rapid eye movement (REM) sleep<\/strong>.<br \/>\nNREM sleep is divided into stages 1, 2, 3, and 4, which represent a continuum of relative depth.<br \/>\nEach has unique characteristics including variations in brain wave patterns, eye movements, and muscle tone.   <\/p>\n<blockquote>\n<h4 align=\"center\">  Melatonin exerts a modulating function on the sleep-wake process<\/h4>\n<\/blockquote>\n<p>The sleep-wake process is regulated by <strong>neurotransmitters and neuromodulators<\/strong>.<br \/>\nThe anatomical structures involved in the regulation of the wake-sleep cycle form a complex neural network that is interconnected with each other.<br \/>\nAmong the excitatory neurotransmitters we find dopamine, norepinephrine, histamine, glutamate and orexins.<br \/>\nLikewise, the most representative inhibitory neurotransmitters are GABA (gamma amino butyric acid), adenosine and histamine.<br \/>\nFinally, the neurotransmitters that exert the most important modulatory functions are acetylcholine, serotonin and melatonin.    <\/p>\n<\/p>\n<h1>\n\t<strong>What can we say about home remedies?<\/strong><\/h1>\n<p>Many times you will have heard that a glass of <strong>warm milk before going to bed<\/strong> improves sleep and relaxes the body.<br \/>\nWell, what was kept as a secret with little scientific rigor, has been demonstrated by a group of scientists through the study that we cite below. <\/p>\n<p><strong> Tryptic casein hydrolysate<\/strong> <strong>(CTH),<\/strong> present in milk, was shown to possess <strong>stress-relieving and sleep-enhancing<\/strong> effects, but only the decapeptide YLGYLEQLLR (\u03b1-CZP) was reported to have shown affinity for the benzodiazepine site of the GABA A receptor. This study aimed to compare the sleep-enhancing effects between CTH and \u03b1-CZP and to explore new sleep-enhancing peptides.<br \/>\nThe results showed that CTH significantly prolonged sleep duration in mice, which was almost twice as long as that of \u03b1-CZP.<br \/>\nThe \u03b1-CZP in CTH degraded more slowly than synthetic \u03b1-CZP; meanwhile, CTH could release other potential sleep-enhancing peptides during gastrointestinal digestion.   <a href=\"https:\/\/doi.org\/10.1021\/acs.jafc.1c03937\" title=\"URL DOI\">https:\/\/doi.org\/10.1021\/acs.jafc.1c03937<\/a><\/p>\n<\/p>\n<h1>\n\t<strong>Functional changes during sleep<\/strong><\/h1>\n<p>During the sleep period, which usually occurs at night, our body undergoes changes in the physiological functions detailed below.<\/p>\n<ul class=\"rteindent1\">\n<li>  Endocrine system<\/li>\n<li>  Cardiovascular system<\/li>\n<li>  Sympathetic nerve activity<\/li>\n<li>  Respiratory system<\/li>\n<li>  Renal system<\/li>\n<\/ul>\n<h2>\n\t<strong>Endocrine system<\/strong><\/h2>\n<p>Endocrine functions such as growth hormone, thyroid hormone, and melatonin secretion are influenced by sleep.<br \/>\nGrowth hormone secretion usually takes place during the first few hours after sleep onset and usually occurs during slow-wave sleep, while thyroid hormone secretion takes place at the end of the night.<br \/>\nMelatonin, which induces drowsiness, probably by reducing an alert effect of the suprachiasmatic nucleus, is influenced by the light-dark cycle and is suppressed by light.  <\/p>\n<\/p>\n<h2>\n\t<strong>Cardiovascular system<\/strong><\/h2>\n<p>Large changes in blood pressure and heart rate occur during sleep and are primarily determined by the activity of the autonomic nervous system.<br \/>\nFor example, there are brief increases in blood pressure and heart rate with K-complexes, awakenings, and large body movements.<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.1007\/978-1-4613-4009-6_5\" target=\"_blank\" rel=\"noopener\">10.1007\/978-1-4613-4009-6_5<\/a>  <\/p>\n<p><strong>Sympathetic nerve activity<\/strong><\/p>\n<p>Sympathetic nerve activity decreases as NREM sleep deepens; however, there is a burst of sympathetic nerve activity during NREM sleep due to the brief increase in blood pressure and heart rate that follows K-complexes. Compared to wakefulness, there is an increase in activity during REM DOI sleep: <a href=\"https:\/\/doi.org\/10.1056\/nejm199302043280502\" target=\"_blank\" rel=\"noopener\">10.1056\/NEJM199302043280502<\/a><\/p>\n<p><strong>Respiratory system<\/strong><\/p>\n<p>Ventilation and respiratory flow change during sleep and become increasingly rapid and erratic, specifically during REM sleep.<br \/>\nData on ventilation during REM sleep are unclear, but they suggest that hypoventilation (poor ventilation of the lungs resulting in reduced oxygen content or increased carbon dioxide content in the blood, or both) occurs in a similar way to NREM sleep.<br \/>\nSeveral factors contribute to hypoventilation during NREM sleep, and possibly REM, such as reduced pharyngeal muscle tone.<br \/>\nIn addition, during REM sleep, rib cage movement is reduced and upper airway resistance increases due to loss of tone in the intercostal and upper airway muscles.     <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0014265\">https:\/\/doi.org\/10.1371\/journal.pone.0014265<\/a><\/p>\n<p><strong>Renal system<\/strong><\/p>\n<p>There is a decrease in the excretion of sodium, potassium, chloride and calcium during sleep which allows for a more concentrated and reduced flow of urine.<br \/>\nThe changes that occur during sleep in kidney function are complex and include changes in renal blood flow, glomerular filtration, hormone secretion, and sympathetic neural stimulation.<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.1152\/ajpregu.1991.261.2.r373\" target=\"_blank\" rel=\"noopener\">10.1152\/ajpregu.1991.261.2.R373<\/a>  <\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"http:\/\/salengei.com\/wp-content\/uploads\/adobestock_253430561.jpeg\" style=\"width: 800px; height: 600px;\"><\/p>\n<h1>\n\t<strong>Melatonin<\/strong><\/h1>\n<p><strong>Melatonin<\/strong>, present in the formulation of <strong><a href=\"http:\/\/salengei.com\/active-sweet-dreams\">Active Sweet Dreams<\/a><\/strong>, is an endogenous hormone produced by the pineal gland <strong>whose synthesis is governed by the light\/dark cycle<\/strong>, i.e. it is inactivated by light and activated by darkness.<br \/>\nThe synthesis of this hormone is carried out from tryptophan which, by hydroxylation and decarboxylation reactions, gives rise to the formation of serotonin and later melatonin. <\/p>\n<p>In hypertensive patients treated with beta-blockers, three weeks of nightly melatonin supplementation significantly improved sleep quality, with no apparent tolerance and no rebound sleep disturbances during discontinuation of melatonin supplementation (in fact, a positive carryover effect was demonstrated).<\/p>\n<blockquote>\n<h4 align=\"center\">\n\t\t<a href=\"http:\/\/salengei.com\/active-sweet-dreams\">Active Sweet Dreams<\/a> contains 1 mg of melatonin per capsule<\/h4>\n<\/blockquote>\n<p><strong>Beta-1 blockers not only reduce sympathetic outflow to the cardiovascular system, but they also block sympathetic signaling to the<\/strong> <strong>pineal gland, resulting in suppression of nighttime levels of the soporific hormone melatonin<\/strong>.<br \/>\nTherefore, melatonin supplementation can potentially counteract the sleep disturbances associated with the use of beta-blockers.  <a href=\"https:\/\/doi.org\/10.5665\/sleep.2122\">https:\/\/doi.org\/10.5665\/sleep.2122<\/a><\/p>\n<p>Various studies have shown that <strong>aging is related to a decrease in the nocturnal synthesis of melatonin<\/strong> , with older adults being the most susceptible to having low levels of this hormone, leading to the appearance of sleep disorders.<\/p>\n<p>Polysomnographic studies consistently show that older people spend more time in bed, sleep less time, take longer to fall asleep, wake up more often and for longer periods of time, and have less efficient sleep.<br \/>\nIn addition, they spend less time in slow-wave sleep, REM sleep, and are more likely to nap compared to younger individuals. <\/p>\n<p>It is important to remember that these changes are age-related and are not the result of any medical or psychiatric pathology, primary sleep disorder, or poor sleep hygiene.<br \/>\nThat is, even in extremely healthy individuals, they manifest sleep disturbances. <a href=\"https:\/\/www.academia.edu\/14148836\/Effective_treatment_of_sleep_disturbances_in_older_adults?pop_sutd=false\">https:\/\/www.academia.edu\/14148836\/Effective_treatment_of_sleep_disturbances_in_older_adults?pop_sutd=false<\/a> <\/p>\n<\/p>\n<h1>\n\t<strong>Valerian<\/strong><\/h1>\n<p>The effect <strong>of the aqueous extract of valerian<\/strong> (Valeriana officinalis L.), which has been present in the Pharmacopoeia for a long time, and which is also present in <strong><a href=\"http:\/\/salengei.com\/active-sweet-dreams\">Active Sweet Dreams<\/a><\/strong>, was studied in 128 people.<br \/>\nEach person received nine samples (3 with placebo, 3 with 400 mg of valerian extract, and 3 with a proprietary over-the-counter valerian preparation).<br \/>\nThe samples, presented in random order, were taken on non-consecutive nights.<br \/>\nValerian produced a <strong>significant decrease in<\/strong> subjectively assessed <strong>sleep latency<\/strong> scores and a <strong>significant improvement in sleep quality<\/strong>; The latter was most noticeable among people who felt they didn&#8217;t get enough or irregular sleep, smokers, and people who thought they normally had long sleep latencies. <a href=\"https:\/\/doi.org\/10.1016\/0091-3057(82)90264-7\" target=\"_blank\" title=\"Persistent binding using digital object identifier\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/0091-3057(82)90264-7<\/a>   <\/p>\n<\/p>\n<h1>\n\t<strong>Rhodiola<\/strong><\/h1>\n<p><strong>Rhodiola rosea<\/strong> (&#8220;golden root&#8221; or &#8220;arctic root&#8221;) is widely distributed at high altitudes in the Arctic and mountainous regions throughout Europe and Asia.<br \/>\nIt is a popular plant in the medical tradition in Eastern Europe and Asia.<br \/>\nIt has a reputation for <strong>stimulating the nervous system, managing depression, improving work performance, eliminating fatigue, and preventing altitude sickness<\/strong>.  <\/p>\n<p>Rhodiola has been categorized as an <strong>adaptogen<\/strong> due to its ability to increase resistance to a variety of chemical, biological, and physical stressors.<\/p>\n<p>The origin of the term adaptogen was coined in 1947 and we owe it to the Russian scientist Lazarev.<br \/>\nLazarev defined an adaptogen as an agent that allows an organism to counteract physical, chemical, or biological stressors by generating non-specific resistance.<br \/>\nThe administration of the adaptogen allows the organism to preadapt, so that it is better able to respond appropriately when demands of various kinds are eventually imposed.<br \/>\nIn 1969, Brekhman and Dardymov proposed criteria that must be met in order to qualify a substance as an adaptogen.   <\/p>\n<ol class=\"rteindent1\">\n<li>  Reduce the damage caused by stressful states, such as fatigue, infection, and depression.<\/li>\n<li>  Have positive excitatory effects on the human body.<\/li>\n<li>  Unlike traditional stimulants, the excitatory effects produced by plant-based adaptogens should not cause side effects such as insomnia, low protein synthesis, or excessive energy intake.<\/li>\n<li>  Demonstrate absence of toxicity and influence on normal body functions.<\/li>\n<\/ol>\n<p>DOI:<a href=\"https:\/\/dx.doi.org\/10.1186%2Fs13020-018-0214-9\" target=\"_blank\" rel=\"noopener\">10.1186\/s13020-018-0214-9<\/a><\/p>\n<\/p>\n<h1>\n\t<strong>Passionflower<\/strong><\/h1>\n<p><strong>Passionflower<\/strong> (Passiflora incarnata) is a large climbing vine with <strong>anxiolytic and tranquilizing activity<\/strong>.<br \/>\nIts traditional use focuses on improving sleep problems and relieving symptoms of mental stress.<br \/>\nA clinical study compared the efficacy of passionflower and oxazepam (30 mg\/day) in 36 outpatients with generalized anxiety for 28 days.<br \/>\nAs a result, oxapezam treatment, despite achieving a faster effect, was not superior in improving anxiety symptoms compared to passionflower treatment.<br \/>\nIn addition, passionflower <strong>has the advantage of not hindering the ability to work<\/strong>.<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.1046\/j.1365-2710.2001.00367.x\" target=\"_blank\" rel=\"noopener\">10.1046\/j.1365-2710.2001.00367.x<\/a>     <\/p>\n<\/p>\n<h1>\n\t<strong>Melissa, Hops and L-theanine<\/strong><\/h1>\n<p><strong>Melissa<\/strong> is used for its dried leaves, whose main components are essential oils (neral, geranial and citronellal), flavonoids and phenolic acids, among which rosmarinic acid stands out.<br \/>\nThe European Pharmacopoeia recommends that the dry extract of the leaf contain a minimum of 2% rosmarinic acid with respect to the dried drug to ensure the quality of lemon balm and preparations containing this plant. <\/p>\n<p>Female inflorescences (strobili) are used from <strong>hops<\/strong> , to which the sedative effect is attributed.<br \/>\nDespite this, the active ingredients responsible for this action are unknown.<br \/>\nThe traditional use of this plant is recommended to fall asleep and relieve mental stress.  <\/p>\n<p><strong>L-theanine<\/strong> is an amino acid obtained from the leaves of green tea (Camellia sinensis) which has a chemical structure similar to that of glutamate, a neurotransmitter related to memory.<br \/>\nThe beneficial effect of L-theanine is based on its ability to bind to GABA receptors increasing their production and, as a consequence, promotes relaxation. <\/p>\n<\/p>\n<p><a href=\"http:\/\/salengei.com\/active-sweet-dreams\"><img decoding=\"async\" alt=\"\" src=\"http:\/\/salengei.com\/sites\/default\/files\/common\/as-_200930-_banner_active_sweet_dreams_0.jpg\" style=\"width: 750px; height: 350px;\"><\/a><\/p>\n<\/p>\n<h1>\n\t<strong>The importance of sleep hygiene<\/strong><\/h1>\n<p>Sleep, like all behavior, must be exercised through good habits.<br \/>\nHere are some points that might be helpful: <\/p>\n<ol>\n<li>  Lie down only when the &#8220;feeling of sleepiness&#8221; appears.<\/li>\n<li>  Establish a relaxation routine every night.<\/li>\n<li>  If you do not fall asleep within the first 30 minutes, get out of bed and do another quiet activity that does not involve screens.<\/li>\n<li>  Establish regular sleep-wake schedules.<\/li>\n<li>  Limit naps to 15-20 minutes.<\/li>\n<li>  Do not perform intense physical exercise in the 3-4 hours before bedtime.<\/li>\n<li>  Do not perform intellectual activity at the time of going to bed.<\/li>\n<li>  Avoid stimulant drinks 6 hours before going to sleep.<br \/>\nThe same with alcohol and tobacco. <\/li>\n<li>  The room should have a cool and comfortable temperature, adequate lighting, and be quiet.<\/li>\n<li>  Do not go to sleep with any screen or visual stimulus.<br \/>\nTurn off all light sources during sleep.   <\/li>\n<\/ol>\n<h1>\n\t<strong>Conclusion<\/strong><\/h1>\n<p>Sleep is a process <strong>that is actively regulated and modulated<\/strong> in a significant way by the homeostatic influences that accumulate during wakefulness and dissipate during rest and by the circadian effects of the day (24 hours).<br \/>\nSleep has a typical underlying architecture characterized by a <strong>rhythmic alternation<\/strong> between the NREM and REM stages, and the transitions between the sleep-wake states are orchestrated by a well-defined subcortical network of brain structures.<br \/>\nSleep-wake states are also characterized by distinct hormonal patterns that exert significant potential influences on glucose metabolism and homeostasis.  <\/p>\n<p><strong><a href=\"http:\/\/salengei.com\/active-sweet-dreams\">Active Sweet Dreams<\/a> <\/strong>It contains the necessary extracts so that a person <strong>who does not have functional, anatomical or psychiatric problems<\/strong>, can relax, fall asleep more quickly and maintain it without the concomitant use of hypnotics, antidepressants or antihistamines.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this post, in addition to focusing on falling asleep through the reduction of latency time, we also consider stress reduction as a necessary action to achieve this.<br \/>\nActive Sweet Dreams contributes to pre-dream relaxation, so important in balance to obtain a conciliatory rest. <\/p>\n","protected":false},"author":3,"featured_media":2708,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-5191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>How to Deal with Sleep Problems - Salengei<\/title>\n<meta name=\"description\" content=\"In this post, in addition to focusing on falling asleep through the reduction of latency time, we also consider stress reduction as a necessary action to achieve this. 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