Hydrolyzed collagen and its benefits on skin, bones and joints

The aging process of the skin is an issue that concerns both men and women and, in recent decades, its prevention and treatment
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The skin aging process is a topic that concerns both men and women and, in recent decades, its prevention and treatment has become a global trend.
In today’s article, we will talk about hydrolyzed collagen and how we can get the most out of its use, not only to show off radiant skin, but also to improve our overall health.

Understanding the context

Skin aging has become a global trend for both men and women.
Individuals of all ages have focused on the care of the largest organ of the human body for various reasons, among which aesthetic and health predominate.

Beyond traditional skin creams, the beauty industry has introduced different products, active ingredients and forms of application over time, until the food industry began to show a growing interest in the subject.
It was then that we saw the birth of a new concept born from the union of the pharmaceutical and food industry that gained notoriety and is still valid today more than ever: nutricosmetics.

Nutricosmetics nourish us from the inside

The analysis of foods and their classification is beyond the scope of this article, but we will only say that nutricosmetics combine a new way of administering active ingredients that have a site of action on the skin and surprise with the results.
But if we dig a little deeper, we will see that with this new type of multipurpose food not only cosmetic results are obtained, but also health, due to the high impact on our body of the peptides obtained from hydrolyzed collagen.

Collagen and its anti-aging effects

Collagen represents a family of 28 proteins that make up a third of the total protein present in our body and plays a key role in the support and structure functions of the different tissues.
All members of this family share a triple helix structure composed of alpha chains.
In turn, a triple helix assembly forms a collagen fibril.
Collagen fibrils are made up of different types of collagen: types I and III are present in the skin and types II and III in cartilage.

Collagen synthesis decreases with age

When we talk about skin aging, basic processes occur that take place in the dermis, a place that topical products do not access.
Some studies have shown that modifying certain aspects of nutrition would have relevant results on the health and appearance of the skin. Remember that the skin is exposed to two types of stimuli that accelerate its deterioration. On the one hand, external factors that affect appearance, such as pollutants present in the environment, ultraviolet radiation from the sun and various climatic factors.
But on the other hand, intrinsic aging is added, which takes place when the speed of cell turnover, the production of collagen and hyaluronic acid, key substances in the maintenance of healthy skin, decreases.
For the purposes of this article, we will leave aside the presence of specific skin diseases and alterations that could modify the appearance.

Scientific reviews on collagen

In 1978, a group of researchers led by Postlethwaite discovered that human collagen peptides type I, II, and III could have a chemotactic effect on fibroblasts.
In addition to the above, di- and tripeptides containing hydroxyproline were also chemotactic for human fibroblasts in vitro.

Based on this discovery, the authors suggested that collagen and collagen-derived peptides could act as a stimulus to attract fibroblasts to a certain site and repair damaged tissues.
DOI: https://doi.org/10.1111/ijd.15518

Hydrolyzed collagen would have beneficial effects on the skin

In addition to the above, other studies have shown that the use of other substances would help reduce tissue damage, acting as adjuvants by improving hydration or preventing damage caused by inflammation.
In this sense, the use of vitamins C and E as antioxidants proved to be of vital importance for the fight against free radicals from reactive oxygen species.
As an additional fact, remember that vitamin C is an essential cofactor and plays a key role in the final stage of collagen biosynthesis.
DOI: 10.4103/2278-019X.146161

In accordance with the above, the consumption of hydrolyzed collagen would have beneficial effects on the skin.
According to three studies conducted in Japan, consuming at least 10 grams of hydrolyzed collagen daily had a visible moisturizing and revitalizing effect on the skin of study participants after 4 weeks from onset.
To demonstrate this, 2.5, 5 and 10 grams of fish-derived collagen were administered to a group of 20 women between 25 and 45 years of age.
The difference with the placebo group was significant in the measurement of the stratum corneum of the skin, especially in subjects over 30 years of age.

Why does it have benefits for the rest of the body?

Bone is made up of several tissues, the main one being bone tissue.
Among its main components we find the different minerals such as calcium and magnesium that form the inorganic matrix of the bone, providing hardness.
Within the organic matrix of bone, 94% is composed of collagen.
Minerals adhere to this collagen structure.
Without this support structure, the bone lacks solidity.

Hydrolyzed collagen also to strengthen bones and joints

In a study carried out on ovariectomized female mice, the diet was supplemented for 12 weeks with hydrolyzed collagen in a proportion of between 10 and 25 g/kg of weight.
The study showed that such supplementation increased osteoblast activity with a clear effect on bone remodeling and a consequent increase in the external diameter of the cortical area of the femur.
DOI: https://doi.org/10.1080/10408398.2015.1038377

Another study conducted on 130 patients with osteoarthritis was administered hydrolyzed collagen, chondroitin, and glucosamine.
After 6 months, the results were significant improvements in pain and locomotor function.
DOI: https://doi.org/10.1080/19390211.2018.1

Bone is a living tissue that is renewed every 80 days.
That is why good nutrition based on collagen peptides and other specific components is needed. Active Procollagen Plus , in addition to collagen peptides (rich in proline and lysine), contains synergistic nutrients that contribute to collagen synthesis and the maintenance of bones, cartilage and connective tissue under normal conditions.
Thanks to its composition, it contributes to the normal formation of collagen and connective tissue, to the normal functioning of bones and cartilage, and to the maintenance of bones in normal conditions.

Active Procollagen Plus contains 5000 mg of Peptan® F5000 LD collagen, a hydrolyzed type I collagen whose source is fish and is of high purity, with a protein content greater than 97%.
Peptan® collagen has a low density molecular weight (5000 Da), and thanks to this, it provides excellent solubility.
It is characterized by its predominance of glycine, proline and hydroxyproline, which represents about 50% of the total amino acid content.
The concentration of glycine and proline is 10 to 20 times higher than in other proteins.
This specific amino acid composition gives it nutrifunctional properties not found in other protein sources.
In addition, Peptan® collagen has been shown to be easy to absorb, digest and use by the body.

Its functions include:

  • Contributes to the prevention of osteoporosis and arthritis
  • Strengthening of bones, muscles, hair, nails and teeth.
  • Improves collagen levels in the skin.
  • It is an excellent supplement for athletes, especially in post-activity.
  • Prevents osteoporosis during the pre- and post-menopausal stages.

Conclusion

In Salengei’s laboratories, we routinely hold team meetings to brainstorm scientifically based health ideas that provide more than just a specific solution.
This is possible because above all things, the word health is present in the minds of our team before any other.

Active Procollagen Plus dietary supplement that helps to strengthen locomotor health

That is why, thinking about strengthening the skin, but also about the health of our customers, we have developed Active Procollagen Plus. This product is also fortified with key vitamins and trace elements, which act synergistically in the maintenance of bone and dermal homeostasis.
Its components are:

  • Calcium from the algae Lithothamnion calcareum.
  • Methylsulfonylmethane (MSM).
    Organic form of sulfur that strengthens connective tissue.
  • Pomegranate Extract (Ellagic Acid) with higher antioxidant value than red wine and green tea.
  • Silicon povenient from bamboo extract.
  • Hesperidin from orange tree extract.
  • Vitamin K in the form of Menakinone 7.
  • Vitamins C and D3.
  • Glucosamine.
  • L-lysine and L-arginine.
  • Hyaluronic acid.
  • Zinc, magnesium, manganese, copper and selenium

We recommend you see the technical sheet of this product through this link.

We hope this article has been of interest to you and we will meet again soon with another publication that sheds light on health, prevention and well-being issues.

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